Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1094/PHYTO.2003.93.4.381 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Structural polymorphism and diversity of human segmental duplications.
Nat Genet
January 2025
Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA.
Segmental duplications (SDs) contribute significantly to human disease, evolution and diversity but have been difficult to resolve at the sequence level. We present a population genetics survey of SDs by analyzing 170 human genome assemblies (from 85 samples representing 38 Africans and 47 non-Africans) in which the majority of autosomal SDs are fully resolved using long-read sequence assembly. Excluding the acrocentric short arms and sex chromosomes, we identify 173.
View Article and Find Full Text PDFPrediction of Patient Drug Response via 3D Bioprinted Gastric Cancer Model Utilized Patient-Derived Tissue Laden Tissue-Specific Bioink.
Adv Sci (Weinh)
January 2025
Center for 3D Organ Printing and Stem cells (COPS), Pohang University of Science and Technology (POSTECH), Pohang, 37666, Republic of Korea.
Despite significant research progress, tumor heterogeneity remains elusive, and its complexity poses a barrier to anticancer drug discovery and cancer treatment. Response to the same drug varies across patients, and the timing of treatment is an important factor in determining prognosis. Therefore, development of patient-specific preclinical models that can predict a patient's drug response within a short period is imperative.
View Article and Find Full Text PDFNutritional niches of potentially endemic, facultatively anaerobic heterotrophs from an isolated Antarctic terrestrial hydrothermal refugium elucidated through metagenomics.
Environ Microbiome
December 2024
Te Aka Mātuatua - School of Science, Te Whare Wānanga O Waikato - University of Waikato, Private Bag 3105, Kirikiriroa - Hamilton, 3240, New Zealand.
Background: Tramway Ridge, a geothermal Antarctic Specially Protected Area (elevation 3340 m) located near the summit of Mount Erebus, is home to a unique community composed of cosmopolitan surface-associated micro-organisms and abundant, poorly understood subsurface-associated microorganisms. Here, we use shotgun metagenomics to compare the functional capabilities of this community to those found elsewhere on Earth and to infer in situ diversity and metabolic capabilities of abundant subsurface taxa.
Results: We found that the functional potential in this community is most similar to that found in terrestrial hydrothermal environments (hot springs, sediments) and that the two dominant organisms in the subsurface carry high rates of in situ diversity which was taken as evidence of potential endemicity.
Neurobehavioral disorders among children born to mothers exposed to illicit substances during pregnancy.
BMC Med
December 2024
National Addiction Centre, Institute of Psychiatry, King's College London, London, UK.
Background: Exposure to illicit substances during pregnancy may have long-term impacts on children's neurodevelopment. This study explores subsequent risks for intellectual disability, autistic disorders, and attention deficit and hyperactivity disorders in children born to mothers exposed to illicit substances before or during pregnancy.
Methods: We identified women with illicit drug use by linking the police records from the "Substance Abuse Control Databases" and Taiwan Birth Registration and Birth Notification records from 2004 to 2014.
Prolonged time from cross clamp until normothermic machine perfusion start is associated with increased risk of early allograft dysfunction following DCD liver transplant.
Liver Transpl
December 2024
Department of Transplant, Mayo Clinic Florida, Jacksonville, Florida.
Introduction: There is a paucity of data on the impact of cold ischemia time prior to the initiation of normothermic machine perfusion (NMP), particularly in more susceptible organs such livers from DCD donors. The present analysis aimed to investigate the impact of prolonged time from cross clamp until NMP start on early allograft dysfunction (EAD) and other peri-liver transplant (LT) outcomes.
Materials: All DCD LT performed and placed on NMP at Mayo Clinic Arizona, Florida and Rochester from January 2022-March 2024 were included.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!