Age-related changes in female skin microrelief (82 nonsmoking and smoking women at the age from 17 to 80 years) were analyzed by the use of VISIOSCAN VS 98. Measurements were taken on inner side of left forearm at the distance of 2 cm away from the bend of elbow. It was demonstrated that such parameters as relievo (V) and roughness (Ser) increased respectively by a factor of 1,23 and 1,50 times in average in group of smoking women of 17 to 28 years old as compared with nonsmoking women of age mate. The statistically valid differences were well documented using the representative samples. On the basis of the results of these studies we can conclude that smoking has a systemic effect on the whole-body skin.
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Int J Cosmet Sci
December 2024
Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Objective: Substantial efforts have been progressively devoted to developing innovative, safe, and effective topical anti-aging products that not only improve the appearance of aged skin but also prioritize environmental sustainability and the responsible use of natural resources. Thus, the current study targeted to evaluate novel, natural emulsion/serum comprising new glycolipid emulsifier (lauryl glucoside/myristyl glucoside/polyglyceryl-6 laurate) and Acmella oleracea plant extract as a model active.
Methods: The developed serum was assessed concerning its stability (freeze-thaw test, accelerated study), safety (in vitro screening of eye irritation potential, dermal absorption study) and efficacy (randomized, active/reference-controlled, half-face, in vivo study).
Int J Cosmet Sci
November 2024
LVMH Recherche, Saint Jean de Braye, France.
Objective: Existing methods to evaluate skin care products suffer limitations. This is the case for ex vivo skin explants, a first-choice 3D model. While essential to analyse mid- to long-term biological effects, this classical model hinders assessing microrelief variations.
View Article and Find Full Text PDFJ Cosmet Dermatol
January 2025
COTY Research and Development, Monaco, Monaco.
Biomimetics (Basel)
June 2024
Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, SK S7N 5C9, Canada.
Skin aging is a complex physiological process, in which cells and the extracellular matrix (ECM) interreact, which leads to a change in the mechanical properties of skin, which in turn affects the cell secretion and ECM deposition. The natural skin microrelief that exists from birth has rarely been taken into account when evaluating skin aging, apart from the common knowledge that microreliefs might serve as the starting point or initialize micro-wrinkles. In fact, microrelief itself also changes with aging.
View Article and Find Full Text PDFPharmaceutics
April 2024
Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-903, Brazil.
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