In search of new erythromycin derivatives 3-O-[gamma-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives have been synthesized. The 3-hydroxy group was derivatised to a primary amine and subsequently the thiazolidinone nucleus was generated at the amino functionality through DCC mediated one-pot three-component reaction in good yields.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486485 | PMC |
| http://dx.doi.org/10.3762/bjoc.4.14 | DOI Listing |
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