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Copper and nickel doped carbon dots for rapid and sensitive fluorescent turn-off detection of bilirubin.
Sci Rep
January 2025
Department of Chemistry, Amrita School of Physical Sciences Coimbatore, Amrita Vishwa Vidyapeetham, Coimbatore, India.
Carbon dots doped with metals and non-metals have gained much popularity due to the enhancement in their optical and electronic properties. In this study, polyethyleneimine-functionalized transition metal (nickel or copper) doped carbon dots (CD, NiCD and CuCD) were synthesized through hydrothermal method. The carbon dots exhibited a blue fluorescence at 470 nm when excited at 350 nm.
View Article and Find Full Text PDFChromium Detection in Water Using Optical Methods: A Study of Reagent and Reagentless Approaches.
Crit Rev Anal Chem
January 2025
Department of Electronics and Communication, Vidyavardhaka College of Engineering, Mysuru, India.
Water contaminated with chromium (Cr) poses significant risks to public health and the environment, necessitating reliable detection techniques. This review study uniquely provides a comprehensive analysis of optical methods for detecting Cr pollution in water, focusing on both reagent-based and reagentless approaches, as well as various sensing platforms. Unlike existing reviews that primarily focus on electrochemical and colorimetric/fluorimetric methods, this work highlights the untapped potential of optical technologies, such as colorimetry, SPR, UV-Vis spectroscopy, and more, in detecting distinct Cr species, including reagent and reagentless based approaches.
View Article and Find Full Text PDFMono--alkylation of Amphotericin B and Nystatin A and Its Amides: Effect on the In Vitro Activity, Cytotoxicity and Permeabilization of Model Membranes.
Antibiotics (Basel)
December 2024
Gause Institute of New Antibiotics, 11 B. Pirogovskaya, Moscow 119021, Russia.
: In 2022, the World Health Organization highlighted the necessity for the development of new antifungal agents. Polyene antibiotics are characterized by a low risk of drug resistance; however, their use is limited by low solubility and severe side effects. : A series of -alkylated derivatives of amphotericin B and nystatin A as well as their -(2-hydroxyethyl)amides were synthesized.
View Article and Find Full Text PDFUltrasensitive analysis of the commonly abused CNS antitussive, dextromethorphan in biological fluids and dosage forms using a novel micellar-sensitized spectrofluorimetric approach: Compliance with greenness and blueness metrics.
Spectrochim Acta A Mol Biomol Spectrosc
December 2024
Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33511, Egypt. Electronic address:
The current study introduces the first micellar-enhanced spectrofluorimetric approach for the estimation of the commonly abused CNS antitussive, dextromethorphan (DXM) in its syrup and biological fluids. A micellar solution of sodium dodecyl sulfate (SDS) containing DXM showed high native fluorescence emission at 305 nm following excitation at 224 nm. Using SDS as a micellar system resulted in about a 2.
View Article and Find Full Text PDFDeveloping a selective and sensitive Fluoride sensing scheme by fluorimetric and chemometric optimisations using highly fluorescent boron-doped Carbon dots with a 'turn off-on' mechanism.
J Fluoresc
December 2024
CSIR-Central Scientific Instrument Organization (CSIO), Chandigarh, India.
Fluoride detection in water is a critical issue that has received extensive attention recently. Researchers have focused on developing practical and reliable methods for detecting Fluoride in water, and fluorescent carbon dots have emerged as a promising solution. These dots are easy to synthesise, highly fluorescent and stable, making them an ideal choice for this application.
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