Background And Objective: To assess the efficacy of a multifactorial intervention at discharge in elderly patients with heart failure to improve the adherence to treatment, reduce readmissions and days of hospitalisation, and to evaluate its effect on quality of life.
Patients And Method: A prospective, randomized clinical trial. Subgroup analysis in elderly patients (older than 70 years) admitted for heart failure. Patients were randomized into 2 groups: intervention and control. The intervention consisted of comprehensive education about the disease, drug therapy, diet, and telephonic strengthening. Rates of readmission, treatment compliance, and quality of life were evaluated at 6 and 12 months postdischarge.
Results: 103 patients were included (53 intervention and 50 control), with a mean age of 79 years and ventricular function predominantly preserved. Both study groups were comparable with regard to baseline sociodemographic and clinical variables. At 6 months, patients in intervention group had a more compliance degree (91.2% vs 68.0%; p = 0.04), were less readmitted (22.6% vs 42.0%; p = 0.03), and number or readmissions/patient (0.3 vs 0.8; p = 0.02) and total days of hospital stay were significantly lower (2.6 vs 5.9;p = 0.01). At 12 months, had a minor number or readmissions without statistical significance. No significant differences were in mortality or quality of life. Survival free from readmissions curves shows that probability of readmission was lower in the intervention group (p = 0.02) with hazard ratio 0.51 (95% confidence interval, 0.27-0.95).
Conclusions: An educative intervention at discharge in an elderly population with heart failure improves treatment compliance, reduces readmissions and hospitalization days, without differences in quality of life.
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http://dx.doi.org/10.1157/13126954 | DOI Listing |
Eur Radiol
January 2025
Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, People's Republic of China.
Purpose: To evaluate the prognostic value of interim [F]Fluorodeoxyglucose positron emission tomography/computed tomography ([F]FDG PET/CT) after immunotherapy-based systemic therapies in extranodal natural killer/T-cell lymphoma (ENKTL).
Patients And Methods: We retrospectively recruited 133 newly diagnosed nasal-type ENKTL patients who underwent interim [F]FDG PET/CT scans after 2-4 cycles of immunotherapy-based treatments. Interim PET/CT was interpreted by maximum standardized uptake value (SUV), Deauville 5-point scale (DS), and early treatment response.
Eur Radiol
January 2025
Department of Ultrasound, First Medical Center, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, 100853, Beijing, China.
Objective: To compare the clinical outcomes between radiofrequency ablation (RFA) and microwave ablation (MWA) for the treatment of T1N0M0 papillary thyroid carcinoma (PTC) in a large cohort.
Materials And Methods: This retrospective study included 1111 patients with solitary T1N0M0 PTC treated with RFA (n = 894) or MWA (n = 215) by experienced physicians. A propensity score matching was used to compare disease progression, including lymph node metastases (LNM), recurrent tumors and persistent tumors, recurrence-free survival (RFS), volume reduction ratio (VRR), and complications between the RFA and MWA groups.
Int Urogynecol J
January 2025
Department of Obstetrics and Gynecology, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, Ningxia, China.
Introduction: Pelvic organ prolapse (POP) is a widespread disease in women. Despite its significant prevalence, there is a lack of comprehensive global studies, emphasizing the urgent need for tailored prevention and treatment approaches. This study aims to examine the global burden of POP from 1990 to 2021 and project future trends using the GBD data.
View Article and Find Full Text PDFInt Urogynecol J
January 2025
Department of Urogynecology and Reconstructive Pelvic Surgery, Atlantic Health System, 435 South Street, Suite 370, Morristown, NJ, 07960, USA.
Introduction And Hypothesis: The objective of our study was to evaluate the need for antibiotic prophylaxis for urinary tract infection (UTI) prevention before Onabotulinum toxin A injection for overactive bladder (OAB). We hypothesize that the lack of antibiotic prophylaxis might not be inferior to administering prophylaxis.
Methods: This was a multi-centered, nonblinded, randomized controlled trial conducted between August 2022 and September 2024.
J Wound Ostomy Continence Nurs
January 2025
Anna Yoo Chang, DNP, FNP-BC, Family Nurse Practitioner, Mayo Clinic, Jacksonville, Florida.
Purpose: The purpose of this quality improvement project was to determine whether hospital-acquired pressure injuries (HAPIs) could be prevented by implementing an educational tool kit for patient care technicians (PCTs).
Participants And Setting: Data were collected from 24 PCTs and 43 patients in a 26-bed inpatient adult acute care unit at an academic medical center in the mid-Atlantic region of the United States.
Approach: Outcome data were collected over an 8-week period from September to November 2021.
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