The authors report an extremely rare case of a patient with acromegaly who had unilateral enlargement of an atlas facet resulting in cord compression and progressive quadriparesis. Although unilateral atlas facet enlargement has been identified in the literature in cases of spondylosis and as a component of congenital malformation, its association with acromegaly has not previously been reported. Resection of the offending facetal bone and atlantoaxial fixation resulted in rapid neurological recovery.
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http://dx.doi.org/10.3171/SPI/2008/9/9/277 | DOI Listing |
Sci Rep
January 2025
Jiangxi Key Laboratory of Molecular Medicine, Jiangxi Medical College, The Second Affiliated Hospital of Nanchang University, Nanchang University, Nanchang, 330006, China.
SMAD3, a protein-coding gene, assumes a pivotal role within the transforming growth factor-beta (TGF-β) signaling pathway. Notably, aberrant SMAD3 expression has been linked to various malignancies. Nevertheless, an extensive examination of the comprehensive pan-cancer impact on SMAD3's diagnostic, prognostic, and immunological predictive utility has yet to be undertaken.
View Article and Find Full Text PDFJ Med Imaging (Bellingham)
November 2024
The NorthCap University, Department of Computer Science and Engineering, Gurugram, Haryana, India.
Purpose: Various brain atlases are available to parcellate and analyze brain connections. Most traditional machine learning and deep learning studies analyzing Attention Deficit Hyperactivity Disorder (ADHD) have used either one or two brain atlases for their analysis. However, there is a lack of comprehensive research evaluating the impact of different brain atlases and associated factors such as connectivity measures and dimension reduction techniques on ADHD diagnosis.
View Article and Find Full Text PDFJ Orthop Case Rep
December 2024
Department of Spine Surgery, Children Hospital Westmead, Sydney, Australia.
Introduction: Death is the most common outcome of longitudinal atlanto-occipital dissociation (L-AOD). Even though rare, survival is commonly seen in the pediatric population. This study reports a successful outcome of a pediatric patient with an L-AOD without neurodeficits, immobilized in a visor (head-neck-chest) orthosis.
View Article and Find Full Text PDFCureus
October 2024
Neurosurgery, Atlas University Medicine Hospital, Istanbul, TUR.
Genome Biol
August 2024
Department of Electrical and Electronic Engineering, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong.
Single-cell atlases pose daunting computational challenges pertaining to the integration of spatial and temporal information and the visualization of trajectories across large atlases. We introduce StaVia, a computational framework that synergizes multi-faceted single-cell data with higher-order random walks that leverage the memory of cells' past states, fused with a cartographic Atlas View that offers intuitive graph visualization. This spatially aware cartography captures relationships between cell populations based on their spatial location as well as their gene expression and developmental stage.
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