An automatic system for acid-base titrations by electrogeneration of H(+) and OH(-) ions, with potentiometric end-point detection, was developed. The system includes a PC-compatible computer for instrumental control, data acquisition and processing, which allows up to 13 samples to be analysed sequentially with no human intervention.The system performance was tested on the titration of standard solutions, which it carried out with low errors and RSD. It was subsequently applied to the analysis of various samples of environmental and nutritional interest, specifically waters, soft drinks and wines.
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http://dx.doi.org/10.1155/S1463924690000323 | DOI Listing |
ERJ Open Res
January 2025
Copenhagen Academy for Medical Education and Simulation, Rigshospitalet, The Capital Region of Denmark, Copenhagen, Denmark.
Rationale: Flexible bronchoscopy is an operator-dependent procedure. An automatic bronchial identification system based on artificial intelligence (AI) could help bronchoscopists to perform more complete and structured procedures through automatic guidance.
Methods: 101 participants were included from six different continents at the European Respiratory Society annual conference in Milan, 9-13 September 2023.
In much of the northern Great Basin of the western United States, rangelands, and semi-arid ecosystems invaded by exotic annual grasses such as cheatgrass () and medusahead () are experiencing an increasingly short fire cycle, which is compounding and persistent. Improving and expanding ground-based field methods for measuring the above-ground biomass (AGB) may enable more sample collections across a landscape and over succession regimes and better harmonize with other remote sensing techniques. Developments and increased adoption of unoccupied aerial systems (UAS) and instrumentation for vegetation monitoring enable greater understanding of vegetation in many ecosystems.
View Article and Find Full Text PDFEng Life Sci
January 2025
Analytical Development & Analytical Attribute Science in Biologics Bristol Myers Squibb Devens Massachusetts USA.
This study emphasizes the critical importance of closely monitoring and controlling the sialic acid content in therapeutic glycoproteins, including EPO, interferon-γ, Orencia, Enbrel, and others, as the level of sialylation directly impacts their pharmacokinetics (PK), immunogenicity, potency, and overall clinical performance due to its influence on protein clearance via hepatic asialoglycoprotein receptors (ASGPR). The ASGPR recognizes and binds to glycoproteins exposed to terminal galactose or N-acetylgalactosamine residues, leading to receptor-mediated endocytosis. Recent studies have demonstrated that sialylation of O-linked glycan plays a role in protecting against macrophage galactose lectin (MGL)-mediated clearance.
View Article and Find Full Text PDFJ Biomed Opt
January 2025
Tel Aviv University, Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv, Israel.
Significance: Imaging flow cytometry allows highly informative multi-point cell analysis for biological assays and medical diagnosis. Rapid processing of the imaged cells during flow allows real-time classification and sorting of the cells. Off-axis holography enables imaging flow cytometry without chemical cell staining but requires digital processing to the optical path delay profile for each frame before the cells can be classified, which slows down the overall processing throughput.
View Article and Find Full Text PDFPNAS Nexus
January 2025
Max Planck Institute for Intelligent Systems, Tübingen 72076, Germany.
Networked datasets can be enriched by different types of information about individual nodes or edges. However, most existing methods for analyzing such datasets struggle to handle the complexity of heterogeneous data, often requiring substantial model-specific analysis. In this article, we develop a probabilistic generative model to perform inference in multilayer networks with arbitrary types of information.
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