The full spectrum technique in the fourier domain was studied for simultaneous determination of Cu(II), Pb(II) and Cd(II) with 4-(2-pyridylazo) resorcinol (PAR). A program called SPGRFSQ. was designed to perform the calculations. Seven error functions were calculated for deducing the number of factors. Data reduction was performed using principal component analysis (PCA) algorithm. Experimental results showed the method to be successful even where there was severe overlap of spectra.
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http://dx.doi.org/10.1155/S1463924695000204 | DOI Listing |
BMC Chem
March 2025
Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Cairo, 11751, Egypt.
Background: Pantoprazole (PAN) is a proton pump inhibitor used to treat GERD and hyperacidity by suppressing gastric acid secretion, effectively relieving symptoms such as heartburn, acid regurgitation, and indigestion. Domperidone (DOM) is a prokinetic agent that enhances gastrointestinal motility, helping to alleviate nausea, vomiting, and bloating caused by motility disorders. Their combination (Pantosec-D) provides rapid and comprehensive relief from both acid-related and motility-related symptoms, significantly improving patient comfort and quality of life.
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March 2025
Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt.
A new combination of silodosin and mirabegron has recently obtained approval in the Indian market for addressing the benign prostatic hyperplasia symptoms associated with overactive bladder syndrome. In this study, we present four validated UV-spectrophotometric methods that rely on straightforward mathematical calculations for the quick and simultaneous assay of MRB and SLD in commercial tablets and synthetic mixes without the need for prior separation. The suggested methods include dual-wavelength, induced dual-wavelength, ratio difference, and area under the curve.
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February 2025
Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Alexandria University, Elmessalah, Alexandria, 21521, Egypt.
A significant variable in the genesis of peptic ulcers is Helicobacter pylori, which could be eliminated through several strategies. Amid them, there is a strategy based on receptor histamine-2 (e.g.
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February 2025
Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo, ET-11562, Egypt.
Carivalan pharmaceutical formulation, which includes carvedilol and ivabradine hydrochloride, is commonly prescribed for alleviating pain associated with angina. Solid contact ion-selective electrodes with wide range of applications have been developed for analysis of these two active ingredients. Those types of electrodes have common drawbacks.
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February 2025
Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo, 11562, Egypt.
Simple, diverse univariate spectrophotometric methods were developed and validated for the determination of amlodipine besylate (AM), perindopril arginine (PE), and indapamide (ID). The first method involved direct measurement of AM absorbance at 365 nm within a concentration range of 2.00-40.
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