[Influence of spontaneous ventricular premature beat coupling interval on the value of heart rate turbulence].

Unlabelled: The heart rate turbulence is promising marker of a sudden cardiac death. The aim of the study is to evaluate the influence of the ventricular premature beat (VPB) coupling interval on the values of turbulence onset (TO) and turbulence slope (TS) parameters in the three groups of patients--"healthy" with ventricular premature beats, pts post myocardial infarction (MI) and pts with chronic heart failure with the left ventricle ejection fraction (LVEF) < 0.35.

Patients And Methods: 382 pts were examined: healthy--149, post MI--123 and LVEF < 0.35 - 110. The distribution ofVPB was analyzed and the values ofTO and TS were evaluated according to the coupling intervals of VPB--in the intervals 00-50, 51-100 (% of RR interval) and in the intervals 34-66 and 67-100 (% of RR interval).

Results: The coupling interval of spontaneous ventricular premature beats cause the statistically significant variability HRT values in all three groups of pts.

Conclusion: The values of TO in the groups of post MI pts and pts with chronic heart failure are higher (risky for sudden cardiac death) after VPB with longer coupling intervals (50-100%, event. 67-100% of RR interval). The TS values are lower (risky for sudden cardiac death) after VPB with longer coupling interval, too. For evaluation of HRT we should use the VPBs with long coupling intervals.