Best sedation practices for pediatric endoscopy involve the consideration of many patient factors, including age, medical history, clinical status, and anxiety level, as well as physician access to anesthesia support. A recent survey of pediatric gastroenterologists suggests that endoscopist-administered intravenous (iv) sedation and anesthesiologist-administered propofol represent common sedation regimens in children. Technical advances in ventilatory monitoring are contributing to increased patient safety for all children undergoing gastrointestinal procedures, regardless of sedation type.
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| http://dx.doi.org/10.1016/j.giec.2008.06.006 | DOI Listing |
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Usefulness and safety of remimazolam in upper gastrointestinal endoscopy: A comparative study between elderly and non-elderly patients.
DEN Open
April 2025
Department of Anesthesiology, Fujimoto General Hospital Miyazaki Japan.
Objectives: In gastroenterology, sedation demand is increasing, although elderly patients are more prone to experiencing adverse events. Remimazolam, a novel ultra-short-acting benzodiazepine, may reduce recovery time after endoscopic procedures.
Methods: This study was a secondary analysis of the investigator-initiated trial, which investigated the efficacy and safety of remimazolam in gastrointestinal endoscopy (REM-IICT JP01).
Remimazolam for Sedation and Trachospray for Topicalization During Flexible Nasal Intubation in a Spontaneously Breathing Patient.
Cureus
January 2025
Anesthesiology and Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, NLD.
When a difficult airway is anticipated, awake tracheal intubation can be considered. Usually, low doses of sedatives are administered during this procedure for minimal sedation and anxiolysis, such as midazolam and remifentanil. The newly developed ultra-short-acting benzodiazepine remimazolam has a pharmacokinetic profile that is more suitable for titration during awake tracheal intubation than the long-acting midazolam.
View Article and Find Full Text PDFRemimazolam, a novel drug, for safe and effective endoscopic sedation.
Clin Endosc
January 2025
Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Korea.
Article Synopsis
- Remimazolam is a new type of benzodiazepine that has rapid onset and short duration, making it great for sedation during endoscopy.
- It presents a safer option compared to older sedatives like midazolam and propofol, with fewer side effects like low blood pressure, heart rate issues, and breathing problems.
- The article highlights remimazolam's benefits, such as easy administration, fast recovery, and low residual sedation, which can enhance patient safety and efficiency in clinical endoscopy.
Introduction: Hypoxaemia is a frequent complication associated with endoscopy conducted under intravenous sedation, highlighting the need for effective and practical interventions. This systematic review aims to evaluate the effectiveness of nasal mask oxygenation in reducing the incidence of hypoxaemia during endoscopy under intravenous sedation compared with the conventional oxygen supply.
Methods And Analysis: This study strictly adheres to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocol guidelines.
Determination of optimal sedation depth in sleep endoscopy with bispectrometry and simultaneous polysomnography.
Eur Arch Otorhinolaryngol
January 2025
Sleep Disorders Center, Ataturk Chest Diseases and Thoracic Surgery Training and Research Hospital, Ankara, Turkey.
Objective: In this study, we aimed to evaluate the localization and configuration of vibration and obstruction in drug-induced sleep endoscopy(DISE) in obstructive sleep apnea patients and to investigate the optimal sedation depth.
Materials And Methods: The study was conducted prospectively with 42 patients. After achieving sedation with intravenous anesthetic agents, simultaneous monitoring of the patient's bispectrometry (BIS), DISE and sleep testing with a type 2 polysomnography device were performed.
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