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Mydriasis Stability During Cataract Surgery in Patients with Systemic Comorbidities Using a Standardised Combination of Intracameral Mydriatics and Anaesthetic.
Life (Basel)
January 2025
University Clinical Centre named after Prof. K. Gibiński, Medical University of Silesia, 40-514 Katowice, Poland.
Background: This study aimed to evaluate mydriasis stability during cataract surgery in patients with systemic comorbidities such as diabetes mellitus (DM) and pseudoexfoliation syndrome (PXF) after a standardised combination of intracameral mydriatics and anaesthetic (SCIMA). Stable mydriasis is crucial for safe and effective phacoemulsification.
Methods: Patients were included if they achieved pupil dilation ≥6.
Can the Dimensional Optimisation of 3D FDM-Manufactured Parts Be a Solution for a Correct Design?
Materials (Basel)
January 2025
Industrial Engineering and Robotics Faculty, Politehnica University of Bucharest, Spl. Independentei 303, 060042 Bucharest, Romania.
Additive manufacturing technology, also known as 3D printing, has emerged as a viable alternative in modern manufacturing processes. Unlike traditional manufacturing methods, which often involve complex mechanical operations that can lead to errors and inconsistencies in the final product, additive technology offers a new approach that enables precise layer-by-layer production with improved geometric accuracy, reduced material consumption and increased design flexibility. Geometrical accuracy is a critical issue in industries such as aerospace, automotive, medicine and consumer goods, hence the importance of the following question: can the dimensional optimisation of 3D FDM-manufactured parts be a solution for correct design? This paper presents a complex study of model parts printed from four common polymers used in fused deposition modelling (FDM) additive technology, namely ABS (acrylonitrile-butadiene-styrene), PLA (polylactic acid), HIPS (high-impact polystyrene) and PETG (polyethylene terephthalate glycol).
View Article and Find Full Text PDFFunctional and Structural Changes in the Inner Ear and Cochlear Hair Cell Loss Induced by Hypergravity.
Int J Mol Sci
January 2025
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Inha University, Incheon 22332, Republic of Korea.
Gravitational changes have been shown to cause significant abnormalities in various body systems, including the cardiovascular, immune, vestibular, and musculoskeletal systems. While numerous studies have examined the response of the vestibular system to gravitational stimulation, research on functional changes in the peripheral inner ear remains limited. The inner ear comprises two closely related structures: the vestibule and cochlea.
View Article and Find Full Text PDFA Comparative Review: Biological Safety and Sustainability of Metal Nanomaterials Without and with Machine Learning Assistance.
Micromachines (Basel)
December 2024
Henan Key Lab of Intelligent Manufacturing of Mechanical Equipment, Zhengzhou University of Light Industry, Zhengzhou 450002, China.
In recent years, metal nanomaterials and nanoproducts have been developed intensively, and they are now widely applied across various sectors, including energy, aerospace, agriculture, industry, and biomedicine. However, nanomaterials have been identified as potentially toxic, with the toxicity of metal nanoparticles posing significant risks to both human health and the environment. Therefore, the toxicological risk assessment of metal nanomaterials is essential to identify and mitigate potential adverse effects.
View Article and Find Full Text PDFIntegrated Proteomic and Metabolomic Analysis of Muscle Atrophy Induced by Hindlimb Unloading.
Biomolecules
December 2024
Department of Aerospace Medical Training, School of Aerospace Medicine, Fourth Military Medical University, Xi'an 710032, China.
Skeletal muscle atrophy, which is induced by factors such as disuse, spaceflight, certain medications, neurological disorders, and malnutrition, is a global health issue that lacks effective treatment. Hindlimb unloading is a commonly used model of muscle atrophy. However, the underlying mechanism of muscle atrophy induced by hindlimb unloading remains unclear, particularly from the perspective of the myocyte proteome and metabolism.
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