This paper describes the oncological experience on 7,216 patients at two cancer units initiated by one medical team in 1975-1977 at Assaf Harofeh Medical Center in Israel (predominantly serving a Jewish population, 4,671 cases) and at the West Bank Cancer Unit (WBCU), which serves an Arab population (2,545 cases). The two centers have the unique feature of serving two populations residing in close geographic proximity but differing in many cultural and socioeconomic characteristics. Data from the ongoing cancer registries in these two centers are summarized and compare the demographic characteristics of the two study groups, anatomic sites of cancer, methods of diagnosis and extent of disease. The findings at the two centers suggest the presence of different risk factors influencing the site distributions of cancers seen in the two populations served. Among the findings, significantly higher (p less than 0.05) estimated relative risks for cancers of the digestive and urinary-genital systems are observed in each sex group at AHMC than at WBCU. Alternatively, the estimated risk of head and neck cancers was significantly higher among both males and females at WBCU compared with their counterparts at AHMC. Differences in risk were also noted for a number of specific anatomic sites of cancer.
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http://dx.doi.org/10.1159/000226947 | DOI Listing |
Ann Med
December 2025
Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Background: Despite the high prevalence of mental stress among physicians, reliable screening tools are scarce. This study aimed to evaluate the capability of the Physician Well-Being Index (PWBI) in identifying distress and adverse consequences among Chinese physicians.
Methods: This cross-sectional online survey recruited 2803 physicians from Southern Mainland China snowball sampling between October and December 2020.
J Am Coll Cardiol
March 2025
National Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.
Background: Transthyretin amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed chronic disease associated with progressive heart failure that results in impaired quality of life, repeated hospitalizations, and premature death. Acoramidis is a selective, oral transthyretin stabilizer recently approved by the U.S.
View Article and Find Full Text PDFBMJ Open
March 2025
Queen Mary University of London, London, UK.
Objectives: Racially minoritised communities (RMCs) were disproportionately affected by COVID-19, experiencing among the highest mortality rates of the UK's pandemic. We sought to understand the priorities for action to address the impact of the COVID-19 pandemic on the health and well-being of RMCs in the ethnically diverse and socioeconomically unequal area of East London, located in the northeastern part of London, England.
Design: Prospective surveys and a consensus meeting following the established James Lind Alliance priority setting partnership (PSP) methodology, adapted for a specific geographic location and ethnic groups.
BMJ Open
March 2025
Key Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong, China
Objective: This study aimed to determine the relationship between occupational noise, shift work and non-alcoholic fatty liver disease (NAFLD) in male workers in the automobile manufacturing industry.
Design: Cross-sectional study.
Setting: This study was carried out at the Guangzhou Twelfth People's Hospital using data from April to September 2022.
Pathol Res Pract
March 2025
Pharmacy college, Al-Farahidi University, Iraq.
The tumor microenvironment (TME) plays a crucial role in the development and progression of gastric cancer (GC). The TME comprises a network of cancer cells, immune cells, fibroblasts, endothelial cells, and extracellular matrix components, which provide a supportive niche for cancer cells. This study investigates the role of TME-derived exosomal competitive endogenous RNAs (ceRNAs), particularly long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs), as major regulating agents in GC development.
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