The interaction of L. pneumophila with lymphoblastoid cell cultures H9 and H9/IIIB and epithelial cell cultures HEp-2 mutual influence have been noted. L. pneumophila penetrates into cells HEp-2 and multiplies there due the so-called "spin phagocytosis". The study of the influence of the preparations of interferon, Leukinferon and Reaferon, on the adhesive capacity of bacteria and their penetration into eukaryotic cells has revealed that the preliminary treatment of both bacteria and cells HEp-2 with the preparations of interferon prior to their infection with Legionella leads to a decrease in the number of microorganisms associated with cells.

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