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Sex-Specific Clinical and Genetic Factors Associated With Adverse Outcomes in Hypertrophic Cardiomyopathy.
Circ Genom Precis Med
January 2025
Garvan Institute of Medical Research, University of New South Wales, Sydney, Australia. (A.B., J.S., A.C., J.I.).
Background: Females with hypertrophic cardiomyopathy present at a more advanced stage of the disease and have a higher risk of heart failure and death. The factors behind these differences are unclear. We aimed to investigate sex-related differences in clinical and genetic factors affecting adverse outcomes in the Sarcomeric Human Cardiomyopathy Registry.
View Article and Find Full Text PDFEvaluation of Outcomes Following Arthroscopic Treatment of Femoroacetabular Impingement Syndrome Across Different Surgeons, Surgical Techniques, and Postoperative Protocols: A Multi-institutional Study.
Orthop J Sports Med
January 2025
Department of Orthopaedic Surgery and Sports Medicine, University of Washington, Seattle, Washington, USA.
Background: Femoroacetabular impingement syndrome (FAIS) is frequently treated arthroscopically with osteoplasty and labral repair. Surgical preferences vary in terms of equipment, technique, and postoperative protocol. Patient-reported outcome measures (PROMs) are valuable tools to assess outcomes across different institutions.
View Article and Find Full Text PDFMethylation of and Are Risk Factors and Potential Biomarkers for Cervical Lesions.
World J Oncol
February 2025
Department of Pathology, The Seventh Medical Center, Chinese PLA General Hospital, Beijing 100700, China.
Background: The correlation between methylation of paired box gene 1 () and sex determining region Y-box 1 () with human papillomavirus (HPV) infection and the progression of cervical lesions is not well understood. This study aims to explore the potential value of and as diagnostic biomarkers for cervical diseases.
Methods: A total of 139 cervical biopsy tissue samples were obtained from the Department of Pathology, the Seventh Medical Center, Chinese PLA General Hospital from 2021 to 2023.
Age- and Sex-Specific Risks of Major Cardiovascular Complications and All-Cause Mortality Following Elective Hip and Knee Arthroplasty in the Netherlands: A Dutch Hospital Data Registry Study.
Arthroplast Today
February 2025
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands.
Background: Age and sex are well-known risk factors for cardiovascular complications and mortality following total hip arthroplasty (THA) and total knee arthroplasty (TKA). Yet, stratified up-to-date absolute risk estimates, which are needed to optimize prevention, are lacking.
Methods: All Dutch patients who had a first primary THA and TKA for osteoarthritis between 2015 and 2021 were included.
Disparities in Trauma Care for Latino Patients: An Analysis by Trauma Center Verification Level.
Cureus
December 2024
Trauma and Acute Care Surgery, Riverside Community Hospital, Riverside, USA.
Introduction Trauma is the leading cause of death for individuals under 45 in the United States (US), with significant disparities in outcomes among minority groups. Latinos, the largest ethnic minority in the US, often face barriers to optimal trauma care that may require additional resources. This study aimed to compare trauma outcomes for Latino patients treated at Level I versus Level II/III trauma centers (TCs).
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