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The management of severe eczema in pregnancy.
Clin Med (Lond)
December 2024
St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust.
Atopic eczema (eczema; also known as atopic dermatitis) is a chronic inflammatory skin condition. The burden of eczema can be very substantial with significant itch, skin pain, secondary infection, sleep disturbance and psychological distress. Eczema is common in pregnancy.
View Article and Find Full Text PDFPreparation of Patchouli Oil Microemulsion Gel and Its Topical Application to Ameliorate Atopic Dermatitis in Mice.
Gels
December 2024
School of Pharmacy, Inner Mongolia Medical University, Hohhot 010100, China.
Patchouli oil (PO) is a natural substance famous for its immune-enhancing and anti-inflammatory effects. Atopic dermatitis (AD) is characterized by epidermal gene mutations, skin barrier dysfunction, and immune dysregulation, making patchouli volatile oil a potential candidate for AD treatment. Initially, PO was mixed with ethyl oleate (EO), castor oil ethoxylated ether-40 (EL-40), anhydrous ethanol, and water to form a patchouli oil microemulsion (PO-ME) system.
View Article and Find Full Text PDFRecomendaciones sobre el uso de productos hidratantes elaboradas por dermatólogos españoles mediante el método Delphi.
Actas Dermosifiliogr
December 2024
Hospital General Universitario Dr. Balmis. ISABIAL, Alicante, España.
Background And Objective: Moisturizing products are widely used in conditions affecting skin hydration. However, the lack of scientific evidence leads to discrepancies and great variability in the recommendations used by different health professionals. The aim of this consensus document is to generate recommendations based on the evidence and experience of dermatologists to unify and facilitate the use of moisturizing products in the routine clinical practice.
View Article and Find Full Text PDFAllergens in ophthalmic medicaments in New Zealand.
Australas J Dermatol
December 2024
Department of Dermatology, Auckland City Hospital, Te Whatu Ora Health, New Zealand.
Background/objectives: Eyelid allergic contact dermatitis (ACD) attributed to ophthalmic medications is often underreported, which can result in poor outcomes. Patch testing for eyelid ACD requires up-to-date knowledge of potential allergens. The aim of this study was to investigate allergens in ophthalmic medicaments in New Zealand.
View Article and Find Full Text PDFPlasma rich in growth factors (PRGFs) has proven potentially beneficial as a bioregenerator in patients with chronic skin disorders due to its anti-inflammatory effect. However, its therapeutic potential may be limited by soluble autoimmune components associated with inflammatory dermatoses in blood plasma. To evaluate the impact of skin health status on cell bioactivity, PRGF was prepared from healthy (H) donors as well as from individuals with atopic dermatitis (AD), psoriasis (PS), or lichen sclerosus (LS).
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