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http://dx.doi.org/10.2169/internalmedicine.47.1408 | DOI Listing |
BMC Nephrol
December 2024
Kidney Disease and Transplant Center, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, 247-8533, Kanagawa, Japan.
Background: Recently, the incidence of caffeine intoxication has been on an upward trend, with severe outcomes. However, acute kidney injury (AKI) resulting from renal pathologies secondary to caffeine intoxication is rare, and the pathophysiological mechanisms underlying AKI are unclear.
Case Presentation: A female patient in her 20s ingested an over-the-counter drug containing caffeine.
Purpose: Cytisine is the active ingredient in preparations used for smoking cessation. Its popularity is attributed to its low cost, efficacy, and low incidence of adverse effects. Additionally, its easy over-the-counter availability is also significant.
View Article and Find Full Text PDFMed Pr
December 2024
Wojewódzki Specjalistyczny Szpital im. dr. Wł. Biegańskiego / Wł. Biegański Regional Specialist Hospital, Łódź, Poland (Oddział Chorób Wewnętrznych i Geriatrii / Department of Internal Medicine and Geriatrics).
Over-the-counter (OTC) drugs taken as intended and according to medical advice are a safe form of disease control. In the public consciousness, they are regarded as harmless agents. Thus, there is a danger of insufficient knowledge about possible side effects, interactions with other drugs or the consequences of taking too high doses.
View Article and Find Full Text PDFCureus
August 2024
Psychiatry, Mayo University Hospital, Castlebar, IRL.
A 51-year-old female, with no previous history of psychosis, presented to the Emergency Department with an acute psychotic episode in the context of excess caffeine consumption. Caffeine is an adenosine antagonist. An antagonist of adenosine can lead to the release of dopamine into the synaptic cleft, which can induce psychotic symptoms in vulnerable individuals.
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