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Alzheimers Dement
December 2024
King's College London, Strand, London, United Kingdom.
Background: The prevalence of dementia in low- and middle-income countries is increasing, yet epidemiological data from African populations remains scarce. Crucial risk factors differ in Africa from more intensively studied global areas, including a high burden of cerebrovascular disease (evidenced by high stroke incidence) and HIV, but lower rates of other risk factors such as physical inactivity. In the pre-antiretroviral therapy era, dementia was a common consequence of HIV infection.
View Article and Find Full Text PDFUsing electronic medical records in hospital simulation for infection control intervention assessment.
Infect Control Hosp Epidemiol
January 2025
One Health Trust, Washington, D.C., USA.
Background: Clinical trials for assessing the effects of infection prevention and control (IPC) interventions are expensive and have shown mixed results. Mathematical models can be relatively inexpensive tools for evaluating the potential of interventions. However, capturing nuances between institutions and in patient populations have adversely affected the power of computational models of nosocomial transmission.
View Article and Find Full Text PDFUnveiling Oral Health Differences: Gingival Health and Hygiene in Children With and Without Cleft Lip and Palate.
Cleft Palate Craniofac J
January 2025
Hospital of Craniofacial Anomalies Rehabilitation, University of São Paulo, Bauru, Brazil.
Objective: To compare the oral hygiene and gingival health of children with and without cleft lip and palate.
Design: Cross-sectional comparative study.
Setting: Institutional tertiary referral hospital.
Efficacy of Cetylpyridinium Chloride Mouthwash on Denture Plaque Reduction and Microbiome Alteration in a Randomized Crossover Trial.
Cureus
December 2024
Department of Prosthodontics, Graduate School of Dentistry, Showa University, Tokyo, JPN.
Purpose This study aimed to evaluate the effectiveness of cetylpyridinium chloride (CPC) mouthwash in reducing denture plaque and its impact on the microbial composition of denture plaque. Materials and methods A randomized, placebo-controlled crossover trial included 29 participants with maxillary complete dentures. Participants used either CPC or a placebo mouthwash for one week each in a crossover design.
View Article and Find Full Text PDFAssessment of Risk Factors Leading to Amputation Among Diabetic Septic Foot Patients in Khartoum, Sudan.
Cureus
December 2024
Trauma and Orthopaedics, Gateshead Health National Health Services (NHS) Foundation Trust, Gateshead, GBR.
Introduction Diabetes is a rapidly growing global health concern, with the World Health Organization (WHO) estimating that 300 million adults will have diabetes by 2025. This chronic condition is associated with complications, including nephropathy, retinopathy, neuropathy, cardiovascular disease, and diabetic foot ulcers (DFUs), which can lead to amputation. Diabetic septic foot (DSF), a severe form of diabetic foot disease, is defined by the WHO as the presence of infection, ulceration, or tissue destruction in the lower limb, often accompanied by neurological abnormalities, peripheral vascular disease, and metabolic complications of diabetes.
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