Objective: The study was conducted to assess how misbeliefs and fears about intrauterine contraceptive devices (IUDs) can influence the rate of early discontinuation of this method.
Study Design: This is a prospective survey conducted at the Family Planning Clinic at Al-Habibia Maternity Teaching Hospital (Baghdad, Iraq). Two hundred women presenting to the family planning clinic with requests for premature IUD removal were administered a structured questionnaire to ascertain demographic information and reasons for removal request. Careful and sympathetic questioning was essential in order to obtain correct information. The data were analyzed using descriptive and inferential statistics.
Results: Slightly over half of the women (52.8%) gave only one reason for requesting removal, while the remaining (47.5%) women had two or three complaints. Side effects were the principal reason for request for removal in both groups (45.7% and 42.6%). In the group that offered only one reason, IUD side effects, device-related issues, fears about the device and pregnancy or seeking pregnancy were the reported reasons. In the group that offered more than one reason, each had two or three complaints. IUD side effects and fears about the device were the most prevalent (42.6% and 41.8%, respectively); these fears and perceptions were reported more frequently among younger users and among those requesting early removal.
Conclusion: Fears and misbeliefs about IUD contributed to discontinuation of use in almost half of the women requesting IUD removal. These elements were more common among younger women and, noticeably, among those who requested early removal.
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http://dx.doi.org/10.1016/j.contraception.2008.05.009 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405.
Dysregulation of GABAergic inhibition is associated with pathological pain. Consequently, enhancement of GABAergic transmission represents a potential analgesic strategy. However, therapeutic potential of current GABA agonists and modulators is limited by unwanted side effects.
View Article and Find Full Text PDFOtol Neurotol
February 2025
Department of ORL-Head & Neck Surgery and Audiology, Odense University Hospital, Odense C, Denmark.
Objective: To investigate the association between postoperative antibiotic prophylaxis and the risk of infections leading to implant explantation or hospitalization, with a follow-up of up to 12 years.
Study Design: Retrospective cohort study.
Setting: Tertiary medical institution.
Br J Dermatol
January 2025
Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, The University of Manchester, Manchester, UK.
Background: The current management of psoriasis does not differentiate between young and old patients in selecting the safest and/or most effective biologic.
Objectives: To explore the effect of age at treatment initiation in response to biologics in patients with moderate-to-severe psoriasis in the UK and Eire.
Methods: Data from patients registering to the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) from 2007-2024 on first course of Tumour Necrosis Factor (TNF), interleukin (IL) 12/13, IL-17 and IL-23 inhibitors (i) with at least 6 months' follow-up were included.
PLoS One
January 2025
Worldwide Health Economics and Outcomes Research, Bristol Myers Squibb, Princeton, NJ, United States of America.
Background: Belatacept is approved for the prophylaxis of organ rejection in Epstein-Barr virus (EBV)-seropositive kidney transplant recipients and is associated with a risk of post-transplant lymphoproliferative disorder (PTLD).
Methods: Data from the Organ Procurement and Transplantation Network were used to examine patterns of belatacept use, describe patient characteristics, and estimate risk of PTLD in EBV-seropositive, kidney-only transplant recipients receiving belatacept- or calcineurin inhibitor (CNI)-based immunosuppression as part of US Food and Drug Administration-mandated safety monitoring.
Results: During the study period (June 15, 2011-June 14, 2016), 94.
J Med Chem
January 2025
Sorbonne Université, CNRS Institut Parisien de Chimie Moléculaire, IPCM, F-75005 Paris, France.
Despite recent advances in cancer treatment, there is still a need for novel compounds with antineoplastic activity. Among 11 biphenyl-based organogold(III) -heterocyclic carbene (NHC) (BGC) complexes of general formula [(C^C)Au(NHC-pyr)X], where (C^C) = 4,4'-ditertbutylbiphenyl, X = Cl or phenylacetylide, and (NHC-pyr) is a pyridyl-substituted NHC ligand, the complex bearing a 4-CF-pyridyl substituent and a chloride ligand showed promising antineoplastic activity on the triple negative breast cancer cell line. was able to induce cell apoptosis but had no effect on the cell cycle.
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