Pachydermoperiostosis (PDP) is a rare hereditary disorder characterized by pachydermia, digital clubbing, arthritis and periosteal hypertrophy. We report the case of a patient with PDP who developed vitiligo. While the association of autoimmune diseases and some dermatological disorders with PDP has been reported before, this appears to be the first described case of vitiligo in association with PDP. The main clinical features of PDP are reviewed and the differential diagnosis is discussed.
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