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Correction: Genome‑wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors.
Acta Neuropathol
January 2025
Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Genome-wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors.
Acta Neuropathol
November 2024
Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Article Synopsis
- Aggressive pituitary neuroendocrine tumors (PitNETs) often grow despite treatment and can metastasize, making them particularly challenging to manage.
- This study analyzed tumor samples from 64 patients to investigate genetic markers, finding distinct patterns between aggressive/metastatic tumors and benign ones through genome-wide methylation and chromosomal analyses.
- The results indicate potential biomarkers that could help in identifying high-risk patients earlier, refining treatment protocols, and improving outcomes for those with aggressive pituitary tumors.
Clinical management and outcome of head and neck paragangliomas (HNPGLs): A single centre retrospective study.
Clin Endocrinol (Oxf)
September 2024
Regional Centre for Endocrinology and Diabetes, Royal Victoria Hospital, Belfast, UK.
Context: Head and neck paragangliomas (HNPGLs) are rare, usually benign, slow-growing tumours arising from neural crest-derived tissue. Definitive management pathways for HNPGLs have yet to be clearly defined.
Objective: To review our experience of the clinical features and management of these tumours and to analyse outcomes of different treatment modalities.
Establishing Normative Values for Healthy Term Infant Feeding Performance: Neonatal Eating Assessment Tool-Mixed, Oral Feeding Scale, and Early Feeding Skills Assessment.
Am J Speech Lang Pathol
November 2023
School of Nursing, University of North Carolina at Chapel Hill.
Purpose: Infants with perceived feeding problems are frequently referred for assessment of their feeding abilities. However, little is known regarding how healthy nondysphagic infants perform on commonly used assessments, making determination of impairment difficult. The aim of this investigation was to elucidate the characteristics of healthy term infant feeding performance using three commonly employed clinical assessments: Neonatal Eating Assessment Tool-Mixed (NeoEat-Mixed), Oral Feeding Scale, and Early Feeding Skills (EFS).
View Article and Find Full Text PDFClinicoradiological outcomes after radical radiotherapy for lung cancer in patients with interstitial lung disease.
BJR Open
April 2023
Cancer Centre Belfast City Hospital, Belfast Health & Social Care Trust, Lisburn Road, Belfast, Northern Ireland.
Objective: Interstitial lung disease (ILD) is relatively common in patients with lung cancer with an incidence of 7.5%. Historically pre-existing ILD was a contraindication to radical radiotherapy owing to increased radiation pneumonitis rates, worsened fibrosis and poorer survival compared with non-ILD cohorts.
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