AI Article Synopsis
- The study analyzes the benefits and risks of (18)F-fluorodeoxyglucose ((18)FDG) PET cancer screening for healthy individuals, focusing on the balance between radiation exposure and cancer detection benefits.
- By using ICRP methods, they estimated the impact of radiation exposure on life expectancy and quantified lifesaving person years from cancer detection.
- Findings suggest that the benefit/risk ratio is favorable for males aged 35-39 and females aged 30-34, indicating ongoing effectiveness in older populations, with further analysis of PET/CT screening needed.
Article Abstract
The benefits of (18)F-fluorodeoxyglucose ((18)FDG) positron emission tomography (PET) cancer screening are expected to include a large population of examinees and are intended for a healthy group. Therefore, we attempted to determine the benefit/risk ratio, estimated risk of radiation exposure, and benefit of cancer detection. We used software that embodied the method of the International Commission on Radiological Protection (ICRP) to calculate the average duration of life of radiation exposure. We calculated the lifesaving person years of benefit to be obtained by (18)FDG PET cancer screening detection. We also calculated the benefit/risk ratio using life-shortening and lifesaving person years. According to age, the benefit/risk ratio was more than 1 at 35-39 years old for males and 30-34 years old for females. (18)FDG PET cancer screening also is effective for examinees older than this. A risk-benefit analysis of (18)FDG-PET/computed tomography (CT) cancer screening will be necessary in the future.
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| http://dx.doi.org/10.6009/jjrt.64.1151 | DOI Listing |
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