Out of 175 pneumococcal isolates from middle ear fluids, 26.3% were penicillin-resistant S. pneumoniae (PRSP). Serotypes 19F and 23F occurred most frequently among PRSP strains. The 7-valent pneumococcal conjugate vaccine (PCV) showed better coverage of PRSP strains (87.0%). The 7-valent PCV may reduce the prevalence of PRSP in Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576607PMC
http://dx.doi.org/10.1128/JCM.01782-08DOI Listing

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