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One-pot catalytic enantioselective domino nitro-michael/michael synthesis of cyclopentanes with four stereocenters. | LitMetric

A highly enantioselective organocatalytic one-pot synthesis of nitro-, formyl-, and ester-functionalized cyclopentanes with four stereocenters is presented. The cyclopentanes were formed as a predominant diasteroisomer and isolated in high yields with 97-99 % ee.

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http://dx.doi.org/10.1002/chem.200801082DOI Listing

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