A total synthesis of (+)-bakkenolide-A was carried out via the key intermediate 4, which was prepared based on an asymmetric cyclization-carbonylation reaction established in our laboratory. Diastereoselective construction of the spirolactone moiety was achieved using Mitsuhashi's protocol as a key step.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1248/cpb.56.1436 | DOI Listing |
Publication Analysis
Top Keywords
conversion optically
4
optically active
4
active hydrindanone
4
hydrindanone +-bakkenolide-a
4
+-bakkenolide-a total
4
total synthesis
4
synthesis +-bakkenolide-a
4
+-bakkenolide-a carried
4
carried key
4
key intermediate
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!