AI Article Synopsis

  • Two new flavonoid glycosides, 3'-(2'',4''-dihydroxybenzyloxy)acanthophorin B (1b) and beta,2,3',4,4',6-hexahydroxy-alpha-(alpha-L-rhamnopyranosyl)dihydrochalcone (2), were isolated from the leaves of Psorospermum androsaemifolium, alongside other compounds like quercetin and acanthophorin B.
  • The structures of these metabolites were determined through spectroscopic analysis and comparisons with existing literature.
  • The compounds exhibited weak antifungal and antibacterial activities.

Article Abstract

Two new flavonoid glycosides, namely 3'-(2'',4''-dihydroxybenzyloxy)acanthophorin B (1b) and beta,2,3',4,4',6-hexahydroxy-alpha-(alpha-L-rhamnopyranosyl)dihydrochalcone (2) were isolated from the leaves of Psorospermum androsaemifolium together with quercetin (1), acanthophorin B (1a), alpha- (3) and beta-amyrine (3a), vismiaquinone (4), 12-hentriacontanol and hentriacontane. The structures of these secondary metabolites were established using detailed spectroscopic analysis and by comparison with published data. Compounds 1, 1a, 1b, 2, 3, 3a and 4 showed weak antifungal and antibacterial activities.

Download full-text PDF

Source
http://dx.doi.org/10.1248/cpb.56.1428DOI Listing

Publication Analysis

Top Keywords

flavonoid glycosides
8
psorospermum androsaemifolium
8
glycosides constituents
4
constituents psorospermum
4
androsaemifolium baker
4
baker clusiaceae
4
clusiaceae flavonoid
4
glycosides 3'-2''4''-dihydroxybenzyloxyacanthophorin
4
3'-2''4''-dihydroxybenzyloxyacanthophorin beta23'44'6-hexahydroxy-alpha-alpha-l-rhamnopyranosyldihydrochalcone
4
beta23'44'6-hexahydroxy-alpha-alpha-l-rhamnopyranosyldihydrochalcone isolated
4

Similar Publications

Duranta erecta Linn. belongs to the Verbenaceae family and is primarily found in subtropical, tropical, and temperate climates. The plant has been reported to contain a variety of phytoconstituents, including iridoid glycosides, flavonoids, flavonoid glycosides, alkaloids, phenolics, tannins, terpenoids, steroids, and saponins.

View Article and Find Full Text PDF

Purpose Of The Review: Clinical trials suggest that dietary anthocyanins may enhance cognitive function. This systematic literature review and meta-analysis aimed to identify the effect of anthocyanin on cognition and mood in adults.

Recent Findings: Using a random-effects model, Hedge's g scores were calculated to estimate the effect size.

View Article and Find Full Text PDF

Linn., commonly known as the 'Tree of Sadness' belongs to Oleaceae family. In Ayurvedic, Siddha, Unani, and Homeopathic therapeutic systems, it has been used to treat various conditions, including ulcers, skin diseases, hair loss, piles, liver diseases, rheumatism, and malarial fevers.

View Article and Find Full Text PDF

Natural flavonoid glycosides Chrysosplenosides I & A rejuvenate intestinal stem cell aging via activation of PPARγ signaling.

Life Med

June 2024

Laboratory of Stem cell and anti-Aging Research, Frontiers Science Center for Disease-related Molecular Network, State Key Laboratory of Respiratory Health and Multimorbidity and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.

The decline in intestinal stem cell (ISC) function is a hallmark of aging, contributing to compromised intestinal regeneration and increased incidence of age-associated diseases. Novel therapeutic agents that can rejuvenate aged ISCs are of paramount importance for extending healthspan. Here, we report on the discovery of Chrysosplenosides I and A (CAs 1 & 2), flavonol glycosides from the Xizang medicinal plant Maxim.

View Article and Find Full Text PDF

Background: Atherosclerosis serves as the fundamental pathology for a variety of cardiovascular disorders, with its pathogenesis being closely tied to the complex interplay among lipid metabolism, oxidative stress, and inflammation. Wogonoside is a natural flavonoid extracted from Scutellaria baicalensis with a variety of biological activities, including anti-inflammatory, hypolipidemic, and cardiac function improvement properties. Despite these known effects, the specific role of wogonoside in the context of atherosclerosis remains to be elucidated.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!