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Factors Associated With False-Positive Recalls in Mammography Screening.

J Natl Compr Canc Netw

February 2023

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Background: We aimed to identify factors associated with false-positive recalls in mammography screening compared with women who were not recalled and those who received true-positive recalls.

Methods: We included 29,129 women, aged 40 to 74 years, who participated in the Karolinska Mammography Project for Risk Prediction of Breast Cancer (KARMA) between 2011 and 2013 with follow-up until the end of 2017. Nonmammographic factors were collected from questionnaires, mammographic factors were generated from mammograms, and genotypes were determined using the OncoArray or an Illumina custom array.

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Breast Cancer Mode of Detection in a Population-Based Cohort.

Mayo Clin Proc

February 2023

Division of General Internal Medicine, Mayo Clinic, Rochester, MN; Department of Internal Medicine, Yale New Haven Health, New Haven, CT. Electronic address:

Objective: To evaluate how breast cancers come to clinical attention (mode of detection [MOD]) in a population-based cohort, determine the relative frequency of different MODs, and characterize patient and tumor characteristics associated with MOD.

Patients And Methods: We used the Rochester Epidemiology Project to identify women ages 40 to 75 years with a first-time diagnosis of breast cancer from May 9, 2017, to May 9, 2019 (n=500) in a 9-county region in Minnesota. We conducted a retrospective medical record review to ascertain the relative frequency of MODs, evaluating differences between screening mammography vs all other MODs by breast density and cancer characteristics.

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Public health advocacy in action: the case of unproven breast cancer screening in Australia.

Public Health Res Pract

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Cancer Council Western Australia, Perth; WA Cancer Prevention Research Unit, Curtin University, Perth, Australia.

In recent years, nonmammographic breast imaging devices, such as thermography, electrical impedance scanning and elastography, have been promoted directly to consumers, which has captured the attention of governments, researchers and health organisations. These devices are not supported by evidence and risk undermining existing mammographic breast cancer screening services. During a 5-year period, Cancer Council Western Australia (CCWA) used strategic research combined with legal, policy and media advocacy to contest claims that these devices were proven alternatives to mammography for breast cancer screening.

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Follow-up of patients with early breast cancer: is it time to rewrite the story?

Crit Rev Oncol Hematol

August 2014

Department of Medical Oncology, IRCCS AOU San Martino-IST, Genova, Italy.

The guidelines for follow-up in breast cancer survivors support only performance of periodic physical examination and annual mammography. However, medical oncologists and primary care physicians routinely recommend both blood tests and non-mammographic imaging tests in asymptomatic patients, leading to an increased anxiety related to false-positive results and higher medical expenses. Recently, advanced imaging technologies have improved sensitivity/specificity to detect metastatic lesions before symptoms arise.

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