Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10557-008-6136-5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mycoplasma pneumoniae-induced Kawasaki disease via PINK1/Parkin-mediated mitophagy.
Exp Cell Res
August 2024
Department of Pediatrics, Fujian Children's Hospital(Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou 350001, PR China; College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fujian Maternity and Child Health Hospital, Fuzhou 350001, PR China. Electronic address:
Kawasaki disease (KD) is a systemic vasculitis with an unknown cause that primarily affects children. The objective of this study was to explore the function and underlying mechanism of mitophagy in Mycoplasma pneumoniae (MP)-induced KD. To create MP-induced KD models, Human coronary endothelial cells (HCAECs) and DBA/2 mice were employed and treated with Mp-Lipid-associated membrane proteins （LAMPs）.
View Article and Find Full Text PDFProtective role of arachidonic acid against diabetic myocardial ischemic injury: a translational study of pigs, rats, and humans.
Cardiovasc Diabetol
February 2024
Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases Beijing Key Laboratory of Pre-Clinical Research and Evaluation for Cardiovascular Implant Materials, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Aim: Patients with diabetes mellitus have poor prognosis after myocardial ischemic injury. However, the mechanism is unclear and there are no related therapies. We aimed to identify regulators of diabetic myocardial ischemic injury.
View Article and Find Full Text PDFA zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons.
Elife
September 2021
Department of Bioengineering and Therapeutic Sciences and Programs in BiologicalSciences and Human Genetics, University of California, San Francisco, San Francisco, United States.
Parkinson's disease (PD) is a common neurodegenerative disorder without effective disease-modifying therapeutics. Here, we establish a chemogenetic dopamine (DA) neuron ablation model in larval zebrafish with mitochondrial dysfunction and robustness suitable for high-content screening. We use this system to conduct an in vivo DA neuron imaging-based chemical screen and identify the Renin-Angiotensin-Aldosterone System (RAAS) inhibitors as significantly neuroprotective.
View Article and Find Full Text PDFMitochondrial PINK1--a novel cardioprotective kinase?
Cardiovasc Drugs Ther
December 2008
The Hatter Cardiovascular Institute, University College London Hospital and Medical School, 67 Chenies Mews, London WC1E 6HX, UK.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!