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Treatment outcome in patients with spinal neurocysticercosis: a systematic review of published cases and case series.
Future Microbiol
November 2024
Department of Neurology, King George's Medical University, Lucknow, India.
Aims: Spinal neurocysticercosis is a rare central nervous system infection caused by the larval form of the . Due to its rarity, most knowledge is derived from isolated case reports. This review aims to evaluate existing case reports and observational studies to provide a comprehensive overview of the disease's clinical presentation and treatment outcomes.
View Article and Find Full Text PDFImmunologic Profiling of CSF in Subarachnoid Neurocysticercosis Reveals Specific Interleukin-10-Producing Cell Populations During Treatment.
Neurol Neuroimmunol Neuroinflamm
November 2024
From the Laboratory of Parasitic Diseases (N.L.T., P.G.-G., L.T., E.M., T.E.N., T.B.N., E.M.O.C.), Integrated Data Sciences Section (P.S., J.L.), National Institute of Allergy and Infectious Diseases; and Clinical Monitoring Research Program Directorate (L.T.), Frederick National Laboratory for Cancer Research.
Background And Objectives: Subarachnoid neurocysticercosis (SANCC) is the most severe form of CNS infection and accounts for the majority of neurocysticercosis-associated mortality. Inflammation is important in the treatment of SANCC because overactivity can lead to serious complications, but excessive suppression may be counterproductive toward parasite eradication. A relative abundance of CSF IL-10 to IL-12 has been associated with increased treatment duration for patients with SANCC, suggesting that IL-10 plays an important role in this disease process.
View Article and Find Full Text PDFSpinal cord compression by cystic IgG4-related spinal pachymeningitis mimicking neurocysticercosis: a case report.
BMC Neurol
September 2024
Division of Neurology, Department of Clinical Medicine, Federal University of Ceara, Prof. Costa Mendes St., 1608, 4th Floor, Fortaleza, 60430-140, Ceara, Brazil.
Background: To report a case of IgG4-related pachymeningitis presenting with cystic lesions mimicking neurocysticercosis.
Case Presentation: A 40-year-old female patient with tetraparesis, dysphagia and dysphonia was evaluated with clinical examination, magnetic resonance imaging, and meningeal biopsy. Magnetic resonance imaging (MRI) revealed diffuse pachymeningeal enhancement involving the cranial, cervical, thoracic, and lumbar segments with spinal cord compression and cystic lesions.
A case-based review on the neuroendoscopic management of intraventricular and subarachnoid basal neurocysticercosis.
Clin Neurol Neurosurg
May 2024
Neurosurgery Unit, "Città della Salute e della Scienza" University Hospital, Turin 10124, Italy.
Objective: Extraparenchymal localization of neurocysticercosis (NCC) is rare in non-endemic areas. A case of mixed (intraventricular, IV, and subarachnoid basal, SAB) NCC was surgically treated using the neuroendoscope and a systematic review of the literature was performed with the aim to analyze the use of this instrument in the management of the extraparenchymal forms of the parasitic disease.
Materials And Methods: Medline and Embase databases were searched for studies where the neuroendoscope was used for the management of IV/SAB NCC cysts, either for the cerebrospinal fluid diversion or cyst removal.
Introduction Infections affecting the central nervous system (CNS) can stem from various sources, including bacteria, viruses, and fungi, manifesting as conditions like meningitis, encephalitis, meningoencephalitis, and brain abscesses. Despite significant advancements in diagnosis and treatment, these infections continue to pose substantial risks to life. Several factors contribute to the causes of CNS infections.
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