Objective: To probe into the mechanisms of moxibustion and Chinese herbs in delaying aging.
Methods: Sixty SD rats were randomly divided into a young control group, an aging group, a moxibustion group, a Chinese herb group and a moxibustion plus Chinese herb group. In the latter 4 groups, aging rat model was established by hypodermic injection of D-galactose. In the course of modeling, the 3 treatment group were treated by mild-warm moxibustion at "Zusanli (ST 36)", "Shenshu (BL 23)" and "Guanyuan (CV 4)" with reinforcing method, stomach perfusion of decoction of Liuwei Dihuang plus Danggui (Angelica) and Danshen (Salvia Miltiorrhiza Bge), and the moxibustion plus the Chinese herbs, respectively. After treatment for 40 days, liver mitochondrial DNA, serum IL-2 and IL-6 contents were detected.
Results: (1) The mitochondrial DNA content of liver cells and serum IL-6 level significantly increased (P < 0.05, P < 0.01) and serum IL-2 level significantly decreased (P < 0.05) in the aging model group as compared with those in the young control group. (2) The mitochondrial DNA content of liver cells and serum IL-6 level significantly decreased (P < 0.05, P < 0.01) and serum IL-2 level significantly increased (P < 0.05) in all the treatment group as compared with those in the aging model group.
Conclusion: Moxibustion and Chinese herbs function delaying aging though decreasing mitochondrial DNA content of liver cells and serum IL-6 level and increasing serum IL-2 level.
Download full-text PDF |
Source |
---|
Curr Mol Med
January 2025
Rehabilitation Department, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou, Hebei 061001, P.R. China.
Sortilin acts as a key receptor for lipids, growth factors, cytokines, and enzymes and participates in pathological cargo loading and transferring of extracellular vesicles. Emerging evidence suggests a significant role of sortilin in hyperlipidemia and the risk of atherosclerosis. Recent epidemiological evidence demonstrated that sortilin has been implicated in atherosclerosis plaque progression in patients with coronary or peripheral artery disease.
View Article and Find Full Text PDFSci Rep
January 2025
Postgraduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Fever has long been recognized as one of the earliest clinical indicators of illness and remains a leading reason for seeking medical care worldwide. It is typically classified based on its duration and underlying etiology. In clinical settings, intractable fever is as common as acute fever, particularly in patients with brain injuries.
View Article and Find Full Text PDFBMJ Open
January 2025
Library, Southern Medical University, Guangzhou, Guangdong, China
Objectives: COVID-19, a public health emergency affecting the world in 2019, not only greatly promoted the development and application of vaccines but also effectively shortened the publishing time of scientific papers. In view of these facts, the current situation, status, problems and development trends of vaccine research and application were explored through bibliometric analysis of highly cited papers in the vaccine field within the time frame of 2014-2024, and the countries, institutions, authors, funding agencies and other relevant information that contributed most to vaccine research and application were summarised.
Design: Bibliometric analysis through data analysis and visual mapping.
J Affect Disord
January 2025
Department of Acupuncture and Moxibustion, The Third Affiliated Hospital of Beijing University of Chinese Medicine, Beijing 100029, China. Electronic address:
Background: Research on the relationship between chest pain and depression risk in patients with or without coronary heart disease (CHD) is limited.
Methods: This cross-sectional study includes adults in the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2018. The diagnoses of chest pain and CHD were based on self-reports from participants, while depressive symptoms were assessed using the Patient Health Questionnaire (PHQ-9).
Brain Behav Immun
January 2025
Department of Acupuncture-Moxibustion and Tuina, Shandong Provincial Third Hospital, Shandong University, Jinan, Shandong, China. Electronic address:
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!