AI Article Synopsis
- Migraine is a common headache disorder affecting 10-12% of people and is a significant cause of worldwide health issues.
- Research indicates a high occurrence of patent foramen ovale (PFO) in migraine patients, particularly those with aura, suggesting PFO might contribute to migraine development.
- Patients with migraines and PFO often report symptom relief after closing the PFO, leading to an exploration of this treatment approach in managing migraines.
Article Abstract
Migraine is a very common type of headache. With a prevalence of 10-12%, migraine ranks 19th among diseases causing worldwide morbidity. Number of studies have shown a high prevalence of patent foramen ovale (PFO) in patients with migraine, especially migraine with aura. The right to left shunting of blood in a PFO could serve as a conduit for chemicals that would exert a trigger effect on hyper excitable neurons leading to the development of migraine. Furthermore patients with PFO and migraine also show a marked improvement in their symptoms after percutaneous closure of the PFO. This review is a close look at this association and also explores whether subsequent closure of the shunt can be looked upon as a viable treatment option.
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