AI Article Synopsis
- p-Hydroxybenzaldehyde, a component found in soil, underwent ozonation and chlorination, revealing mutagenic activities through the Ames assay.
- Non-ionic resin CSP800 and anion exchange resin CHPA25 were used for separating mutagenic compounds, but water layer compounds showed strong mutagenicity and were not adsorbed.
- Increasing chlorine levels reduced mutagenic activity, while GC-MS analysis identified several mutagenic compounds such as chloral and tetrachloroethylene in the ether extracts.
Article Abstract
p-Hydroxybenzaldehyde, a component of soil humic substances, was ozonated and chlorinated. The ether extract and the residue were subjected to the Ames assay; mutagenic activities were identified. The non-ionic resin CSP800 and the anion exchange resin CHPA25 were used for separation of mutagenic compounds. The compounds in the water layer were not adsorbed on CSP800 or CHPA25 and exhibited strong mutagenic activity. Mutagenic activity was reduced as the added chlorine was increased. Ether extracts were analyzed by gas chromatography-mass spectrometry (GC-MS) and chloral, 1,3-dichloro-2-propanone, 1,2,3-trichloro-1-propene, tetrachloroethylene and 1,1,1,3,3-pentachloro-2-propanone were identified as mutagenic compounds.
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| http://dx.doi.org/10.1016/0048-9697(91)90140-a | DOI Listing |
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