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[Perioperative management with consumption of alcohol and nicotine in patients with hip and knee arthroplasty].
Orthopadie (Heidelb)
December 2024
Klinik für Orthopädie und Unfallchirurgie, Zentralklinik Bad Berka, Robert-Koch-Allee 9, 99438, Bad Berka, Deutschland.
Excessive consumption of nicotine and alcohol has been proven to effect the organ system. Both stimulants are consumed in the population to a not insignificant extent. The question therefore arises as to what effect the consumption of nicotine and alcohol has on the complication rates and to what extent this should be reduced or stopped before performing a joint arthroplasty? A literature search was carried out to answer these questions.
View Article and Find Full Text PDFEvaluating the impact of Canadian cannabis legalization on cannabis use outcomes in emerging adults: Comparisons to a US control sample via a natural experiment.
Int J Drug Policy
December 2024
Peter Boris Centre for Addictions Research, St. Joseph's Healthcare Hamilton and McMaster University, Canada; Michael G. DeGroote Centre for Medicinal Cannabis Research, McMaster University and St. Joseph's Healthcare Hamilton, Canada.
Background: Recreational cannabis legalization marked a significant policy shift in Canada, but has been difficult to evaluate because of the absence of a control group. Although it is unfeasible to evaluate legalization using a randomized controlled trial design, sophisticated statistical techniques can employ quasi-experimental designs using natural experiments. This study evaluates the impact of cannabis legalization in a longitudinal cohort of Canadian emerging adults by comparing changes in cannabis use frequency and related consequences over time to changes in a similar cohort in a United States jurisdiction where no policy change took place.
View Article and Find Full Text PDFAssociations of the Korean patient placement criteria matching among individuals with alcohol-related problems with treatment completion and abstinence: an observational study.
Addict Sci Clin Pract
December 2024
Department of Psychiatry, Hanyang University Hospital, 222 Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea.
Background: The American Society of Addiction Medicine Patient Placement Criteria (ASAM PPC) are guidelines for matching addiction patients to an optimal level of care (LOC). South Korea lacked a systematic approach to assigning alcohol use disorder patients to suitable treatment. To address this, Park et al.
View Article and Find Full Text PDFA multimodal neuroimaging study of youth at risk for substance use disorders: Functional magnetic resonance imaging and [F]fallypride positron emission tomography.
Alcohol Clin Exp Res (Hoboken)
December 2024
Integrated Program in Neuroscience, McGill University, Montreal, Quebec, Canada.
Background: Adolescent alcohol use is the norm, but only some develop a substance use disorder. The increased risk might reflect heightened mesocorticolimbic responses to reward-related cues but results published to date have been inconsistent.
Methods: Young social drinkers (age 18.
Moderate prenatal alcohol exposure alters GABAergic transmission and the actions of acute alcohol in the medial central amygdala of adolescent rats.
Neuropharmacology
December 2024
Department of Psychology, Center for Development and Behavioral Neuroscience, Binghamton University, Binghamton NY 13902, United States; Developmental Exposure Alcohol Research Center, Binghamton NY 13902, United States. Electronic address:
Individuals with prenatal alcohol exposure (PAE) are at a higher risk for developing alcohol use disorder (AUD). Using a rat model of moderate PAE (mPAE) on gestational day 12 (G12; ∼2 trimesters in humans), a critical period for amygdala development, we have shown disruptions in medial central amygdala (CeM) function, an important brain region associated with the development of AUD. In addition to this, acute ethanol (EtOH) increases GABA transmission in the CeM of rodents in a sex-dependent manner, a mechanism that potentially contributes to alcohol misuse.
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