Background: To examine the effects of (1) examinee gender on United States Medical Licensing Examination (USMLE) Step 1 performance, (2) examinee gender on the relationships between prematriculation measures and Step 1 performance, and (3) medical school characteristics on the relationships between examinee characteristics and Step 1 performance.
Method: A series of hierarchical linear models (examinees-nested-in-schools) was conducted predicting Step 1 scores. The sample included 66,412 examinees from 133 U.S. Liaison Committee on Medical Education-accredited medical schools/campuses.
Results: Controlling for prematriculation measures, men outperformed women slightly on Step 1. Undergraduate science grade point averages were more associated with Step 1 performance for women than men. Schools with higher mean Medical College Admission Test (MCAT) science scores had higher mean Step 1 scores, and MCAT science scores were slightly more associated with Step 1 performance for students from schools with higher percentages of female students.
Conclusions: Patterns of gender-related performance differences on Step 1 generally mirrored those reported in earlier research. School-level variables provided some additional insight into these relationships, but additional research is needed to fully understand why men and women perform differently on the USMLE.
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http://dx.doi.org/10.1097/ACM.0b013e318183cd65 | DOI Listing |
EJNMMI Phys
January 2025
Department of Nuclear Medicine, Lanzhou University Second Hospital, Lanzhou, 730030, China.
Purpose: The aim of the study was to investigate the value of SwiftScan Step-and-Shoot Continuous (SSC) scanning mode in enhancing image quality and to explore appropriate scanning parameters for reducing scan time.
Methods: This study was composed of a phantom study and two clinical tests. The differences in visual image quality scores, coefficient of variance (COV) of the background, image signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and recovery coefficient (RC) of the sphere were compared between SSC mode and traditional Step-and-Shoot (SS) mode in the phantom study.
Anal Methods
January 2025
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Ministry of Education), School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430072, China.
In this work, a hydrophilic Eu-based ratiometric fluorescent nanosensor (PAAC-Eu) was developed for Cu ion detection in aqueous solutions and imaging in living cells. The sensor was prepared a simple one-step reaction at room temperature, leveraging the synergistic coordination of commercially accessible polyacrylic acid (PAA) and coumarin-3-carboxylic acid (CCAH) with Eu ions. PAAC-Eu was easy to disperse in aqueous media and exhibited two characteristic emission bands at 406 nm and 618 nm, respectively, upon excitation at 350 nm.
View Article and Find Full Text PDFJ Clin Microbiol
December 2024
Chrono-environnement UMR6249, CNRS, University of Franche-Comté, Besançon, Bourgogne-Franche-Comté, France.
Unlabelled: The aim of this study was to identify parameters influencing DNA extraction and PCR amplification efficiencies in an attempt to standardize Mucorales qPCR. The Fungal PCR Initiative Mucorales Laboratory Working Group distributed two panels of simulated samples to 26 laboratories: Panel A (six sera spiked with Mucorales DNA and one negative control serum) and Panel B (six Mucorales DNA extracts). Panel A underwent DNA extraction in each laboratory according to the local procedure and were sent to a central laboratory for testing using three different qPCR techniques: one in-house qPCR assay and two commercial assays (MucorGenius and Fungiplex).
View Article and Find Full Text PDFJ Clin Microbiol
December 2024
Department of Pediatrics, University of Florida, Gainesville, Florida, USA.
Cholera rapid diagnostic tests (RDTs) are vulnerable to virulent bacteriophage predation. We hypothesized that an enhanced cholera RDT that detects the common virulent bacteriophage ICP1 might serve as a proxy for pathogen detection. We previously developed a monoclonal antibody (mAb) to the ICP1 major capsid protein.
View Article and Find Full Text PDFMicrobiol Spectr
December 2024
Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Vaginitis is the most common problem afflicting women of childbearing age. However, the underlying etiological factors remain poorly understood, leading to recurrent vaginitis and constraining clinical management. Here, we explored whether the gut microbiota influences the risk of vaginitis by performing a two-sample Mendelian randomization analysis using the largest genome-wide association studies to date.
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