Impulse air waves (IAW) applied in non-destructive and weakly destructive intensities reduced the activity of lysosomal and microsomal enzymes as well as the activity of adenylate cyclase in the liver of laboratory rats. Five times repeated single application of IAW in intensities causing no noticeable biochemical (and morphological) changes led to shifts in the activity of rat hepatic enzymes. IAW which failed to produce a biological effect in humans when applied separately, inhibited noticeably antipyrine biotransformation in volunteers when applied repeatedly 80 times. It is concluded that the action of repeated subthreshold IAW is additive in character.

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