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Nutrition Care in Cancer: An Overlooked Part of Patient-Centered Care.
Semin Oncol Nurs
January 2025
Bavarian Cancer Research Center and CCC Munich LMU, LMU Hospital Munich, Germany.
Objectives: Robust evidence highlights the crucial role of nutrition for people with cancer, and international organizations recognize it as a basic human right linked to health and food. Within this context, we aim to emphasize the critical role of nutrition care for cancer patients and to highlight the essential contributions of nurses in providing patient-centered nutrition care.
Methods: This opinion paper synthesizes evidence and perspectives from peer-reviewed articles and position papers.
Purpose: In prostate and breast cancer, moderate hypofractionation (HF) has demonstrated comparable, if not greater, efficacy than conventional fractionation. There is a stark disparity in the uptake of HF between North America and Africa. Using the Consolidative Framework for Implementation Research, we evaluated barriers and facilitators for implementing HF in Sub-Saharan Africa (SSA).
View Article and Find Full Text PDF[Research and prospect of application of artificial intelligence technology in oral and maxillofacial surgery].
Zhonghua Kou Qiang Yi Xue Za Zhi
January 2025
Department of Stomatology, The Second Affiliated Hospital of Nanchang University,Nanchang330006, China.
Artificial intelligence (AI) technology is a scientific and technological field that focuses on the research and development of systems that simulate, extend, and expand human intelligence activities. This field encompasses various applications such as image recognition, language processing, expert systems, and robotics. The advancement of AI has greatly improved the quality and efficiency of medical work, particularly in areas like medical imaging, clinical decision support, precision medicine, and healthcare management.
View Article and Find Full Text PDFTargeting molecular pathways to control immune checkpoint inhibitor toxicities.
Trends Immunol
January 2025
Heidelberg University, Medical Faculty Heidelberg, Department of Dermatology and National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and University Hospital Heidelberg, Heidelberg, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ) Core Center Heidelberg, 69120 Heidelberg, Germany. Electronic address:
Immune checkpoint inhibitors (ICIs) have transformed cancer treatment but are frequently associated with immune-related adverse events (irAEs). This article offers a novel synthesis of findings from both preclinical and clinical studies, focusing on the molecular mechanisms driving irAEs across diverse organ systems. It examines key immune cells, such as T cell subsets and myeloid cells, which are instrumental in irAE pathogenesis, alongside an in-depth analysis of cytokine signaling [interleukin (IL)-6, IL-17, IL-4), interferon γ (IFN-γ), IL-1β, tumor necrosis factor α (TNF-α)], integrin-mediated interactions [integrin subunits αITGA)4 and ITGB7], and microbiome-related factors that contribute to irAE pathology.
View Article and Find Full Text PDFA collaborative approach to advancing research and training in Public Health Data Science-challenges, opportunities, and lessons learnt.
Front Public Health
December 2024
Mailman School of Public Health, Columbia University, New York, NY, United States.
The unprecedented availability of increasingly complex, voluminous, and multi-dimensional data as well as the emergence of data science as an evolving field provide ideal opportunities to address the multi-faceted public health challenges faced by low and middle income countries (LMIC), especially those in sub-Saharan Africa. However, there is a severe lack of well-trained data scientists and home-grown educational programs to enable context-specific training. The lack of human capacity and resources for public health data analysis as well as the dire need to use modern technology for better understanding and possible intervention cannot be dealt with currently available educational programs and computing infrastructure, demanding a great deal of collaboration and investments within Africa and with the Global North This paper describes processes undertaken to establish sustainable research training programs and to train a new generation of data scientists with knowledge, mentoring, professional skills, and research immersion.
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