The pyridazinone ring system serves as an excellent scaffold for the diastereoselective preparation of novel cis-fused cyclopentapyridazinones utilizing the directed 5-exo radical cyclization approach. This overall approach was successfully employed in the preparation of a functionalized aza-spirocycle.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745910 | PMC |
| http://dx.doi.org/10.1021/ol801849u | DOI Listing |
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