Multiple compression fractures of osteoporotic vertebrae are common in patients with a liver transplant or with chronic liver disease. The authors describe two such patients, treated with percutaneous cement vertebroplasty at 12 levels, respectively in 4 and in 2 sessions. No complications were seen after follow-up periods of 12 and 8 months respectively. However, this is not a grant for the future, and further followup is necessary. Multiple-level cement vertebroplasty should not be generalized before further experience is gained. Moreover, medical treatment continues to play an important role.

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