Background: The Berlin Questionnaire [an outcome of a primary care physicians' conference held in Berlin, Germany, in 1996 that was created to identify patients at high risk for sleep disordered breathing (SDB)] was administered to a representative sample of middle-age population in Puerto Rico in order to document the prevalence of SDB and its associated risk factors.
Materials And Methods: The island was divided in six regions to maintain heterogeneity and to have a representative sample of the population per region. Puerto Rican subjects between 30-60 years old were recruited in shopping malls, and questionnaires were filled. For each subject, body weight, neck circumference, and height were measured. Information regarding the diagnosis of hypertension was based upon a positive or negative response from study subject in a questionnaire. Data was collected for 6 months.
Results: A total of 290 subjects, all of Puerto Rican origin, were interviewed. Fifty-eight percent of the evaluated sample was found at high risk of SDB. Being male, hypertensive, and obese were the strongest risk factors for the development of SDB. In women, a neck size above 15 cm was a significant risk factor.
Conclusions: This is the first time a prevalence study for SDB is done among a representative sample of subjects of Puerto Rican origin. It is the first step in documenting how SDB affects this ethnic group.
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http://dx.doi.org/10.1007/s11325-008-0216-4 | DOI Listing |
Neurol Clin Pract
October 2024
Department of Neurology (AM, YB, SLP), David Geffen School of Medicine; Institute for Society and Genetics (AM); Interdepartmental Undergraduate Neuroscience Program (AM), UCLA; Division of General Internal Medicine (ACO), Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO; Department of Neurology (YB), Cedars Sinai Health Center, Los Angeles, CA; and Division of General Internal Medicine and Health Services Research (AB), Department of Medicine, David Geffen School of Medicine, UCLA.
Background And Objectives: There are well-documented racial and ethnic disparities in access to neurologic care and disease-specific outcomes. Although contemporary clinical and neurogenetic understanding of Huntington disease (HD) is thanks to a decades-long study of a Venezuelan cohort, there are a limited number of studies that have evaluated racial and ethnic disparities in HD. The goal of this study was to evaluate disparities in time from symptom onset to time of diagnosis of HD.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Department of Epidemiology and Biostatistics, University of California, San Francisco.
Importance: Incidence of distant stage prostate cancer is increasing in the United States. Research is needed to understand trends by social and geographic factors.
Objective: To examine trends in prostate cancer incidence and mortality rates in California by stage, age, race and ethnicity, and region.
Hum Brain Mapp
February 2025
Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA.
Neurodegeneration is presumed to be the pathological process measure most proximal to clinical symptom onset in Alzheimer Disease (AD). Structural MRI is routinely collected in research and clinical trial settings. Several quantitative MRI-based measures of atrophy have been proposed, but their low correspondence with each other has been previously documented.
View Article and Find Full Text PDFAIDS Care
January 2025
Westat, Rockville, MD, USA.
Transgender youth are disproportionately affected by HIV, particularly minoritized youth in the US south. To understand HIV service use among transgender youth, we interviewed 25 young racial and ethnic minority clients of four southern community-based HIV service organizations (CBOs), and CBO staff ( = 12), about service access and use. Participants were assigned male at birth and identified as female ( = 8), transgender ( = 11) or gender-fluid or nonbinary ( = 6).
View Article and Find Full Text PDFAcute lymphoblastic leukemia (ALL) is the most common childhood cancer, with Hispanic/Latino children having a higher incidence of ALL than other racial/ethnic groups. Genetic variants, particularly ones found enriched in Indigenous American (IA)-like ancestry and inherited by Hispanics/Latinos, may contribute to this disparity. In this study, we characterized the impact of IA-like ancestry on overall ALL risk and the frequency and effect size of known risk alleles in a large cohort of self-reported Hispanic/Latino individuals.
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