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Placental transmogrification of the lung presenting as a cystic airspace with an endophytic nodule.
Asian J Surg
October 2023
Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
Congenital Lung Anomalies in Adults.
Radiographics
September 2024
From San Lucas Diagnóstico, 25 de Mayo 1941, 3300, Posadas, Argentina (M.M.N.); Department of Radiology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina (G.D.); Department of Radiology, University of Texas Health Science Center, San Antonio, TX (C.S.R.); Departments of Radiology (R.K., N.R., D.V.) and Pathology (N.S.), University of Colorado Anschutz Medical Campus, Aurora, CO; and Department of Radiology, Hospital San Juan de Dios, HT Médica, Córdoba, Spain (J.B.).
Congenital lung anomaly (CLA) refers to a rare group of malformations that are typically identified prenatally or in early childhood. However, a significant proportion of cases evade detection until adulthood and either are incidentally discovered or manifest with symptoms of recurrent respiratory infection or pulmonary hemorrhage. While most CLAs have characteristic imaging findings at CT and MRI, they remain a diagnostic challenge due to the infrequency with which they are encountered in adults.
View Article and Find Full Text PDFPlacental Transmogrification of the Lung Presenting as Cystic-Solid Mass: A Case Report.
Clin Respir J
July 2024
Department of Respiratory and Critical Care Medicine, The First People's Hospital of Yunnan Province, Kunming, China.
The gradually progressive solitary cystic-solid mass of chest CT scans is highly suggestive of lung cancer. We report a case of a 29-year-old woman with a persistent cystic-solid lesion in the right upper lobe. A chest CT scan showed a 35 mm × 44 mm × 51 mm focal cystic-solid mass in the anterior segment of the right upper lobe.
View Article and Find Full Text PDFIs There a Baby in the Lung? A Case of Placental Transmogrification of the Lung.
J Investig Med High Impact Case Rep
June 2024
Department of Pulmonary and Critical Care, University of Massachusetts, Springfield, USA.
Article Synopsis
- Pulmonary nodules are common in lung-related medical practice, with causes ranging from infection to cancer, and an unusual condition known as placental transmogrification of the lung (PLC) being exceedingly rare.
- PLC typically presents as single lesions in asymptomatic males, but this case is unique as it involves a young female with bilateral nodules.
- The identified nodules in this patient were larger than typical PLC cases and demonstrated growth over an 8-year period, which is uncommon for this condition.
AP-1-dependent fibrosis: Exploring its potential role in the pathogenesis of placental transmogrification of the lung (PTL) via tissue-level transcriptome analysis.
Pathol Res Pract
June 2024
Department of Paediatric Surgery, Hacettepe University, Faculty of Medicine, Ankara, Turkey.
Placental transmogrification of the lung (PTL) is a rare pulmonary condition characterized by the presence of immature placental villous structures. The etiology and molecular mechanisms underlying this disease remain largely unknown. This functional study aimed to identify the molecular signatures in the pathogenesis of PTL via comprehensive transcriptome analysis.
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