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Impact of antiviral prophylaxis on EBV viremia and posttransplant lymphoproliferative disorders in solid organ transplant recipients: a systematic review and meta-analysis.
Virol J
January 2025
Department of Pharmacotherapy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Introduction: Organ transplant recipients face a substantial risk of developing posttransplant lymphoproliferative disorders (PTLD). In over 90% of cases with B-cell PTLD following solid organ transplantation, the Epstein-Barr virus (EBV) genome is promptly identified, usually within the initial year. A continuing discussion revolves around the efficacy of antiviral prophylaxis in mitigating the incidence of PTLD in solid organ transplant (SOT) patients.
View Article and Find Full Text PDFMethotrexate fixed dosing protocol for ambulatory treatment of ectopic pregnancy.
Reprod Sci
January 2025
Rock Creek Medical Office, Kaiser Permanente Colorado, 280 Exempla Circle, Lafayette, Denver, CO, 80516, USA.
The primary objective of this study was to review a methotrexate 90-mg fixed-dose protocol for treatment of ectopic pregnancy, and to evaluate if any characteristics were associated with ectopic pregnancy treatment failure. This was a single arm retrospective cohort study conducted at Kaiser Permanente Colorado. The primary outcome was to describe rates of ectopic pregnancy treatment failure among patients who received fixed dose(s) of methotrexate for ectopic pregnancy between January 1, 2007 and August 31, 2017.
View Article and Find Full Text PDFLight-driven in-situ synthesis of nano-sulfur and graphene oxide composites for efficient removal of heavy metal ions.
J Hazard Mater
January 2025
State Key Lab of Geohazard prevention & Geoenvironment protection, College of Materials and Chemistry & Chemical Engineering, Chengdu University of Technology, Chengdu 610059, China. Electronic address:
Sulfur nanoparticles (SNPs) and their composites are promising for heavy metal adsorption, yet current SNPs often lack surface S, leading to low affinity toward heavy metal and ease of aggregation. Here, we report a simple light-driven method for facile prepare SNPs with surfaces enriched with S and in-situ load them onto graphene oxide (GO) to fabricate GO-S composites. Under illumination, the O generated by photosensitizer phloxine B was able to oxidize S into elemental SNPs.
View Article and Find Full Text PDFThe predictive value of prostate spherical volume ratio in lower urinary tract symptoms and clinical progression of benign prostatic hyperplasia: a retrospective cohort study.
Int Urol Nephrol
January 2025
Department of Urology, School of Medicine, Shanghai East Hospital, Tongji University, No. 150 Jimo Road, Pudong New District, Shanghai, 200120, China.
Purpose: To evaluate the predictive value of Prostate Spherical Volume Ratio for Lower urinary tract symptoms and clinical progression of Benign prostatic hyperplasia. And compared with other prostatic anatomical parameters.
Methods: A total of 154 patients with Benign prostatic hyperplasia who underwent MRI and urodynamics were included in the study, while prostate anatomical parameters such as prostate spherical volume ratio, prostate volume, intravesical prostatic protrusion, prostatic urethral length and presumed circle area ratio were determined based on MRI measurements.
Current insights on PSMA PET/CT in intermediate-risk prostate cancer: a literature review.
Ann Nucl Med
January 2025
Department of Biomedical Sciences, Humanitas University, Milan, Italy.
The purpose of this systematic review was to evaluate the role of PSMA PET/CT in intermediate-risk prostate cancer (PCa) patients, to determine whether it could help improve treatment strategy and prognostic stratification. A systematic literature search up to May 2024 was conducted in the PubMed, Embase and Scopus databases. Articles with mixed risk patient populations, review articles, editorials, letters, comments, or case reports were excluded.
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