AI Article Synopsis
- Saccharomyces cerevisiae extract (SCE) is highlighted for its potential to reduce oxidative stress and improve skin conditions in cosmetic formulations.
- The study tested four different formulations: a control (F1), a formulation with vitamins (F2), one with SCE (F3), and a combination of both (F4), on volunteers to assess their dermatological effects.
- Findings indicated that formulations with SCE (F3 and F4) had significant long-term benefits on skin microrelief and moisture, while the combination of vitamins and SCE (F4) also led to slight irritation in one volunteer, emphasizing the need for careful evaluation in cosmetics development.
Article Abstract
Saccharomyces cerevisiae extract (SCE) is used in cosmetics since it can act in oxidative stress and improve skin conditions. This study investigated dermatological effects of cosmetic formulations containing SCE and/or vitamins A, C and E. The formulation studied was supplemented or not (F1: vehicle) with vitamins A, C and E esters (F2) or with SCE (F3) or with the combination of vitamins and SCE (F4). Formulations were patch tested on back skin of volunteers. For efficacy studies, formulations were applied on volunteers and transepidermal water loss (TEWL), skin moisture (SM), skin microrelief (SMR) and free radicals protection were analysed after 3h, 15 and 30 days of application. Volunteers were also asked about efficacy perception. It was observed that F4 provoked a slight erythema in one volunteer. All formulations enhanced forearm SM. Only F3 and F4 presented long term effects on SMR and showed higher texture values; F3 had the highest brightness values. Our results suggest that vitamins and SCE showed effects in SM and SMR. Only formulations containing SC had long term effects in the improvement of SMR. Thus, these kinds of evaluations are very important in cosmetics development to evaluate the best risk and benefit correlation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.fct.2008.08.028 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Proteomics Reveals Mechanisms of Delayed Keratoconus Progression: A Study of Corneas Following Two Light-Activated Crosslinking Treatments.
Invest Ophthalmol Vis Sci
January 2025
University Eye Clinic Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands.
Article Synopsis
- This study investigates the biological changes in rabbit corneas caused by two light-activated corneal stiffening methods: riboflavin with UVA and WST11 with NIR.
- Differentially expressed proteins were identified following treatments, showing RF-D/UVA affected cell metabolism and keratocyte differentiation, while WST-D/NIR influenced extracellular matrix regulation.
- The findings reveal a metabolic shift towards glycolysis in RF-D/UVA treated corneas compared to normal respiration in WST-D/NIR treated corneas, highlighting the distinct biological effects of each treatment.
Pediatric Teledermatology in the General Teledermatology Practice: Population Variances in Contrasting Health Care Scenarios.
Telemed J E Health
January 2025
Hospital Digital, Célula de Teledermatología, Ministerio de Salud de Chile, Santiago, Chile.
Pediatric dermatology access is limited. Pediatric teledermatology (TD) opens the opportunity to explore diverse dermatological pathology promptly. Different TD modalities and providers may influence the consulting population.
View Article and Find Full Text PDFAnti-melanogenic effects of hydroxyethyl chrysin through the inhibition of tyrosinase activity: and approaches.
Heliyon
January 2025
Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, 56212, Republic of Korea.
The suppression of tyrosinase (TYR), a key enzyme in melanogenesis, has been suggested as an effective strategy for preventing melanin accumulation. We previously discovered the novel chrysin derivative hydroxyethyl chrysin (HE-chrysin) through an irradiation technique, which exerted higher anti-inflammatory and anti-cancer activities than original chrysin. In the present study, we explored whether HE-chrysin has antioxidant and anti-melanogenic capacity using B16F10 murine melanoma cells and molecular docking.
View Article and Find Full Text PDFCase Report: Diagnosis and treatment of with central nervous system anomalies in one patient.
Front Pediatr
January 2025
Department of Pediatrics, The Second Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
Introduction: This article reports a detailed case of a patient with who exhibited epileptic status and dermatologic symptoms.
Case Presentation: A 5-month-old female patient was brought to our hospital due to status epilepticus, with erythematous vesicular skin lesions on her trunk and extremities. Routine magnetic resonance imaging revealed infarction, ischemia, and encephalomalacia.
Transdermal patch based on pressure-sensitive adhesive: the importance of adhesion for efficient drug delivery.
Expert Opin Drug Deliv
January 2025
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, China.
Introduction: Transdermal patches offer a unique advantage by providing extended therapeutic benefits while maintaining stable plasma drug concentration. The efficacy and safety of patches depend significantly on their ability to adhere to the skin, a feature influenced by various external and internal factors.
Areas Covered: The review primarily focuses on the fundamental aspects of adhesion in transdermal patches, including basic information about the skin, the underlying principles of adhesion, drug delivery, and adhesion characteristics of pressure sensitive adhesives (PSAs), adhesion issues, impact factors, strategies to improve patch adhesion, and relevant molecular mechanisms.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!