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Reninoma: an unusual cause of growth failure.
J Pediatr Endocrinol Metab
December 2024
Department of Endocrinology and Diabetes, Max Super Speciality Hospital, Saket, Delhi, India.
Introduction: Growth failure can result from various underlying causes, necessitating a thorough evaluation. Reninoma, a rare renin-secreting tumor, is an uncommon cause of hypertension, especially in paediatric patients, and has not been associated with growth failure until now.
Case Presentation: An 11-year-old girl presented with complaints of poor height gain, headaches, increased thirst, and vomiting.
Successful Management of a Renin-Secreting Tumor in Pregnancy: A Case Report.
Cureus
November 2024
Obstetrics and Gynecology, Osaka Red Cross Hospital, Osaka, JPN.
Article Synopsis
- - A 28-year-old pregnant woman developed severe hypertension early in her pregnancy due to a renin-secreting renal tumor, which was a rare cause of hypertension during this stage.
- - After being hospitalized for blood pressure management and diagnosed with a tumor, she underwent a robot-assisted partial nephrectomy at 16 weeks, which eliminated her hypertension.
- - The successful outcome, with the delivery of a healthy baby at 40 weeks, highlighted the importance of early intervention, medication, and careful monitoring for pregnant women experiencing hypertension.
Tcf21 as a Founder Transcription Factor in Specifying Foxd1 Cells to the Juxtaglomerular Cell Lineage.
Am J Physiol Renal Physiol
November 2024
Division of Pediatric Nephrology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Renin is crucial for blood pressure regulation and electrolyte balance, and its expressing cells arise from Foxd1+ stromal progenitors. However, factors guiding these progenitors toward renin-secreting cell fate remain unclear. Tcf21, a basic helix-loop-helix (bHLH) transcription factor, is essential in kidney development.
View Article and Find Full Text PDFJuxtaglomerular Cell Tumor With Cytohistological Correlation: A Case Report.
Diagn Cytopathol
November 2024
University of Virginia School of Medicine Inova Campus, Falls Church, Virginia, USA.
Juxtaglomerular cell tumors (JCT) are uncommon renin-secreting tumors of the kidney with cytologic findings of JCT rarely reported. We describe a case of JCT in a 37-year-old man with uncontrolled hypertension that was cured by removal of the tumor via partial nephrectomy. Cytology material was prepared by scraping of the freshly sectioned tumor mass and stained with Diff-Quik and Papanicolaou stains.
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