Hypogonadotropic hypogonadism: a consequence of Chiari-I malformation.

Pituitary

Department of Endocrinology, Leeds Teaching Hospitals NHS Trust, D Floor, Brotherton Wing, Leeds General Infirmary, Great George Street, Leeds, UK.

Published: June 2010

AI Article Synopsis

  • Chronic hydrocephalus, often caused by aqueduct stenosis, can lead to changes in menstrual cycles, notably primary and secondary amenorrhea.
  • There have only been six documented cases of secondary amenorrhea linked to this condition.
  • A specific case is presented where a woman with cystic fibrosis developed secondary amenorrhea due to Chiari-I malformation and hydrocephalus, with recovery observed after a 3rd ventriculostomy procedure.

Article Abstract

Chronic hydrocephalus, most commonly the result of aqueduct stenosis, is associated with both primary and secondary amenorrhea. Only six cases of secondary amenorrhea have been reported to date. We describe a women with cystic fibrosis who presented with secondary amenorrhea as a consequence of Chiari-I malformation and resultant hydrocephalus. The biochemical picture was characterized by hypogonadotropic hypogonadism. Resolution of the amenorrhea was observed to occur following 3rd ventriculostomy.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11102-008-0142-2DOI Listing

Publication Analysis

Top Keywords

secondary amenorrhea
12
hypogonadotropic hypogonadism
8
consequence chiari-i
8
chiari-i malformation
8
hypogonadism consequence
4
malformation chronic
4
chronic hydrocephalus
4
hydrocephalus commonly
4
commonly result
4
result aqueduct
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!