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| http://dx.doi.org/10.1111/j.1468-0009.2008.00526.x | DOI Listing |
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Does Merit-based Incentive Payment System Performance Differ Based on Orthopaedic Surgeon Gender?
Clin Orthop Relat Res
December 2024
Department of Orthopedic Surgery, Mayo Clinic, Phoenix, AZ, USA.
Background: Value-based care payment and delivery models such as the recently implemented Merit-based Incentive Payment System (MIPS) aim to both provide better care for patients and reduce costs of care. Gender disparities across orthopaedic surgery, encompassing reimbursement, industry payments, referrals, and patient perception, have been thoroughly studied over the years, with numerous disparities identified. However, differences in MIPS performance based on orthopaedic surgeon gender have not been comprehensively evaluated.
View Article and Find Full Text PDFClinical control in COPD and therapeutic implications: The EPOCONSUL audit.
PLoS One
January 2025
Pulmonology Department, Department of Medicine, Hospital Clínico San Carlos, School of Medicine, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), CIBER de Enfermedades Respiratorias (CIBERES), Universidad Complutense de Madrid, Madrid, Spain.
Objective: This study aimed to evaluate clinical control in chronic obstructive pulmonary disease (COPD), the consequences in terms of treatment decisions, and their potentially associated factors during follow-up of patients in real-life clinical practice.
Methods: EPOCONSUL 2021 is a cross-sectional audit that evaluated the outpatient care provided to patients with a diagnosis of COPD in respiratory clinics in Spain and multivariable logistic regression models to assess the relationships between clinical control and clinical inertia.
Results: 4225 patients from 45 hospitals in Spain were audited.
Biomarkers.
Alzheimers Dement
December 2024
National Center for Geriatrics and Gerontology, Obu City, Aichi, Japan.
Background: Cognitive reserve (CR) is a property of the brain trait that allows for better-than-expected cognitive performance, relative to the degree of brain change over the life course. However, the neurophysiological markers of CR require further investigation. Electroencephalography (EEG) may provide an appropriate neurophysiological marker of CR.
View Article and Find Full Text PDFBackground: By age 40 years, adults with Down syndrome (DS) develop Alzheimer's disease (AD) pathology and progress to dementia in their 60s. Despite minimal systemic vascular risk factors, individuals with DS have MRI evidence of cerebrovascular injury that progresses with AD severity, suggesting an intrinsic vascular component to DS-AD that may interact with neuroinflammatory processes to promote tau pathology and cognitive decline. In the current study we examined whether cerebrovascular disease (CVD) burden and inflammation/astrocytosis independently and interactively were associated with incident diagnosis among adults with DS.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, and the New York Presbyterian Hospital, New York, NY, USA.
Background: Small vessel cerebrovascular disease (CVD), visualized as white matter hyperintensities (WMH) on magnetic resonance imaging (MRI), is associated with risk and progression of Alzheimer's disease (AD) in clinical, community, and genetic studies of AD. However, it is unclear whether these observations indicate a role of CVD in AD pathogenesis. One approach towards understanding whether there is a mechanistic or fundamental function of CVD in AD pathogenesis is by examining whether genetic risk factors for AD are also associated with WMH.
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