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Comprehensive epidemiology of melanoma at all sites: insights from Japan's National Cancer Registry, 2016-2017.
Int J Clin Oncol
January 2025
Rare Cancer Center, National Cancer Center, Tokyo, Japan.
Background: Melanoma is a highly malignant cancer responsible for 55 000 deaths worldwide annually. Despite its severity, its epidemiology in Japan remains understudied owing to its rarity among Asians. This study aimed to determine the incidence of melanoma in Japan using data from the National Cancer Registry.
View Article and Find Full Text PDFCYFIP2: potential pancreatic cancer biomarker and immunotherapeutic target.
Discov Oncol
December 2024
The First Affiliated Hospital of Nanchang University, Nanchang University, 17 Yongwai Zhengjie, Donghu District, Nanchang, 330006, People's Republic of China.
Objective: It has been shown that the CYFIP2 (Cytoplasmic FMR1-interacting protein 2) gene is apoptosis p53-dependent and is associated with poor prognosis in malignant tumors such as gastric cancer and other and cervical cancer. However, the prognostic potential of CYFIP2 in pancreatic cancer remains unclear. In this work, we first explain the great potential of CYFIP2 malignant progression from a broader perspective (pan-cancer) and confirm its oncogenic value in pancreatic cancer.
View Article and Find Full Text PDFComments on EFSUMB recommendations, role of ultrasound in cutaneous neoplasms.
Med Ultrason
November 2024
Clinic of Dermatology and Venerology, Cluj-Napoca County Hospital, Cluj-Napoca.
The European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) has been publishing guidelines, position papers and also technical reviews. In addition, comments have been published for illustration of such papers including the hepatobiliary system, pancreas, lung and other organs. In the current paper, we aim to summarize the typical sonographic findings of the most commonly seen cutaneous neoplasms.
View Article and Find Full Text PDFA rare case report of renal clear cell carcinoma with multiple skin metastases and a review of the literature.
Front Oncol
December 2024
Department of Ultrasound, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Renal cell carcinoma is the most common type of primary renal cancer, and clear cell carcinoma is the most common subtype, accounting for approximately 70% of all adult renal cell carcinoma cases. At the time of diagnosis, many patients already have metastatic manifestations. Cutaneous metastasis of renal clear cell carcinoma is very rare and usually represents a poor prognosis, mostly affecting the head and neck.
View Article and Find Full Text PDFDeucravacitinib shows superior efficacy and safety in cutaneous lupus erythematosus compared to various biologics and small molecules - A systematic review and meta-analysis.
Autoimmun Rev
December 2024
Department of Dermatology, Venereology and Dermatooncology, Faculty of Medicine, Semmelweis University, 41 Mária Street, Budapest 1085, Hungary; Centre for Translational Medicine, Semmelweis University, 22 Baross Street, Budapest 1085, Hungary. Electronic address:
Background: Novel therapies for cutaneous lupus erythematosus (CLE) and systemic lupus erythematosus (SLE) demonstrated efficacy and safety in previous trials. However, data on the comparison of these treatments is still lacking, limiting their integration into clinical practice. Therefore, our aim is to perform a systematic review and network meta-analysis to compare the efficacy and safety of novel systemic therapies in CLE.
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