Aim: Presentation of a new technique to determine the plane of symmetry of a face, and to assess the degree of facial symmetry in patients with unilateral cleft lip and palate based on three-dimensional (3D) optical surface data.
Patients And Methods: After having determined a plane of symmetry according to optical 3D facial surface data, we identified differences in landmarks, the surface areas of the upper lip vermilion and nostrils and virtual volumes of the midface, nose and upper lip for cleft and unaffected sides in forty 10-year-old patients suffering from complete unilateral cleft lip, alveolus and palate. The children had undergone lip repair via the Tennison-Randall technique and had received subsequent orthodontic treatment (but not secondary osteoplasty).
Results: Statistically significant differences were apparent between cleft and non-cleft sides in terms of the nasal landmarks, nostril angle and virtual volume of the nose. The upper lip was symmetrical when cleft and non-cleft sides were compared.
Conclusions: This new technique of symmetry analysis reveals that the noses of 10-year-old patients with complete unilateral cleft lip and palate who had not undergone revisional surgery present a measurable and significant degree of asymmetry, while the upper lip is symmetrical as a consequence of interdisciplinary treatment by orthodontists and oral and maxillofacial surgeons. Further 3D analyses on larger numbers of patients will allow more comprehensive and consistent analysis of the potential and limitations of various surgical and conservative methods so as to identify those techniques with the best outcome in terms of facial symmetry.
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http://dx.doi.org/10.1007/s00056-008-0746-1 | DOI Listing |
Oral Radiol
January 2025
Faculty of Dentistry, Department of Oral and Maxillofacial Radiology, Istanbul University, Istanbul, Turkey.
Objectives: This study evaluates the potential of pulp volume/total tooth-volume measurements of canine teeth in relation to chronologic age in patients with cleft lip and palate (CLP). The significance of this study lies in its exploration of the usability of these measurements for age determination in CLP patients, providing a novel perspective to the existing literature.
Methods: Cone beam computed tomography images of 33 patients (16 females, 17 males) with unilateral CLP aged 14-45 years and 33 age- and sex-matched healthy individuals (16 females, 17 males) were retrospectively evaluated.
In Vitro Cell Dev Biol Anim
January 2025
Department of Oral and Maxillofacial Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250012, Shandong, China.
Cleft lip and palate (CL/P) are prevalent congenital anomalies with complex genetic causes. The G874A mutation of T-box transcription factor 22 (TBX-22) gene is notably associated with CL/P, while the underlying mechanism remains to be clarified. Studies have shown that the restriction of epithelial-mesenchymal transformation (EMT) process in medial edge epithelial cells (MEEs) is crucial for CL/P development.
View Article and Find Full Text PDFPLoS One
January 2025
Escuela de Odontología, Universidad Internacional del Ecuador, Quito, Ecuador.
Background: Monitoring hospitalization rates associated with oral health conditions is an important part of epidemiological surveillance, especially when these conditions have increased significantly in low-and middle-income countries. This study aimed to evaluate the temporal trends in hospital discharges associated with oral health-related conditions in Ecuador from 2000 to 2023 and identify the leading diagnoses groups.
Methods: An ecological time-series study was conducted based on annual data from the National Institute of Statistics and Censuses of Ecuador.
Int J Clin Pediatr Dent
December 2024
Department of Prosthodontics, Crown & Bridge and Implantology, Government College of Dentistry, Indore, Madhya Pradesh, India.
Aims And Background: The study of the morphology of soft tissues as well as hard tissues of the orofacial region holds prime importance. A very less information is known about the lips (soft tissues) and maxillo-mandibular arches (hard tissue structures) in primary dentition. Henceforth, there is a need to classify, find the prevalence and correlation of various lip shapes, and arch forms in primary dentition.
View Article and Find Full Text PDFCureus
December 2024
Department of Orthodontics and Dentofacial Orthopedics, Government Dental College, Thiruvananthapuram, Thiruvananthapuram, IND.
Introduction Unilateral cleft lip and palate (UCLP) often leads to maxillary hypoplasia and skeletal Class III malocclusion, with conflicting evidence on mandibular asymmetry. This study evaluated vertical mandibular asymmetry in UCLP patients, comparing them with non-cleft individuals having skeletal Class III and Class I malocclusions. Methods Mandibular asymmetry was evaluated using orthopantomograms (OPGs) from 90 subjects divided into three groups of 30 each: UCLP group, non-cleft skeletal Class III, and non-cleft skeletal Class I.
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