The effect of Mie resonances on trapping in optical tweezers.

Opt Express

Centre for Biophotonics and Laser Science, School of Physical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.

Published: September 2008

We calculate trapping forces, trap stiffness and interference effects for spherical particles in optical tweezers using electromagnetic theory. We show the dependence of these on relative refractive index and particle size. We investigate resonance effects, especially in high refractive index particles where interference effects are expected to be strongest. We also show how these simulations can be used to assist in the optimal design of traps.

Download full-text PDF

Source
http://dx.doi.org/10.1364/oe.16.015039DOI Listing

Publication Analysis

Top Keywords

optical tweezers
8
interference effects
8
mie resonances
4
resonances trapping
4
trapping optical
4
tweezers calculate
4
calculate trapping
4
trapping forces
4
forces trap
4
trap stiffness
4

Similar Publications

How SNARE proteins generate force to fuse membranes.

Biophys J

January 2025

Department of Chemical Engineering, Columbia University, New York, NY 10027. Electronic address:

Membrane fusion is central to fundamental cellular processes such as exocytosis, when an intracellular machinery fuses membrane-enclosed vesicles to the plasma membrane for contents release. The core machinery components are the SNARE proteins. SNARE complexation pulls the membranes together, but the fusion mechanism remains unclear.

View Article and Find Full Text PDF

High-resolution fluorescence imaging of ultracold atoms and molecules is paramount to performing quantum simulation and computation in optical lattices and tweezers. Imaging durations in these experiments typically range from a millisecond to a second, significantly limiting the cycle time. In this work, we present fast, 2.

View Article and Find Full Text PDF

DEAD-box RNA-dependent ATPases are ubiquitous in all domains of life where they bind and remodel RNA and RNA-protein complexes. DEAD-box ATPases with helicase activity unwind RNA duplexes by local opening of helical regions without directional movement through the duplexes and some of these enzymes, including Ded1p from Saccharomyces cerevisiae, oligomerize to effectively unwind RNA duplexes. Whether and how DEAD-box helicases coordinate oligomerization and unwinding is not known and it is unclear how many base pairs are actively opened.

View Article and Find Full Text PDF

Probing the interaction of mannose-binding lectin with healthy and sickle cell anemia red blood cells and its role in cellular biomechanics.

Int J Biol Macromol

January 2025

Departamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco, Recife, Pernambuco 50670-901, Brazil. Electronic address:

Mannose-binding lectin (MBL) is an important glycoprotein of the human innate immune system. Furthermore, individuals with sickle cell anemia (SCA) and MBL deficiency seem more susceptible to vaso-occlusive crises, suggesting an MBL role on HbSS red blood cells (RBCs). This study investigated the interaction of MBL with HbA (healthy) and HbSS RBCs using optical tweezers (OT) and atomic force microscopy (AFM).

View Article and Find Full Text PDF

The reactivation of heterotrimeric protein phosphatase 2A (PP2A) through small molecule activators is of interest to therapeutic intervention due to its dysregulation, which is linked to chronic conditions. This study focuses on the PP2A scaffold subunit PR65 and a small molecule activator, ATUX-8385, designed to bind directly to this subunit. Using a label-free single-molecule approach with nanoaperture optical tweezers (NOT), we quantify its binding, obtaining a dissociation constant of 13.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!