It is currently unclear if there are modified DNA bases in Trypanosoma brucei other than J-base. We identify herein a cytosine-5 DNA methyltransferase gene and report the presence and location of 5-methylcytosine in genomic DNA. Our data demonstrate that African trypanosomes contain a functional cytosine DNA methylation pathway.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583544 | PMC |
| http://dx.doi.org/10.1128/EC.00198-08 | DOI Listing |
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