Background: Congenital oral and labial melanotic macules are the leading causes of hyperpigmented lesions of the oral mucosa in adults. Although they usually appear in the second decade of life, there are rare reports of these phenomena in children. Congenital lingual melanotic macules have been recently identified as a peculiar and benign cause of hyperpigmentation of the tongue in newborn babies and infants.
Case Reports: We describe the cases of five infants presenting with smooth brown macules of the dorsum of the tongue, measuring several millimetres and detected either at birth or a few days after birth. No history of trauma, medication or similar lesions in relatives was found. Surgical excision of the lesions was performed in two cases. Clinical follow-up in the three other children showed no changes in the lesions in the first two and lightening of the brown macules in the third.
Discussion: Congenital lingual melanotic macules represent a clinically distinct and benign cause of hyperpigmentation of the oral mucosa. They may be more common than the literature suggests, especially among dark-skinned subjects.
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http://dx.doi.org/10.1016/j.annder.2008.07.012 | DOI Listing |
J Am Acad Dermatol
January 2025
Mayo Clinic Arizona, Department of Dermatology, Scottsdale, AZ, USA.
Traditionally, dermatological education emphasizes hair, skin and nails in its curriculum. There is a practice gap with regard to knowledge of normal oral mucosa variants, performance of the oral examination, and competence in diagnosing and treating oral mucosal disorders. The oral mucosa falls within the purview of dermatology.
View Article and Find Full Text PDFJ Am Acad Dermatol
November 2024
Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Department of Dermatology, Harvard Medical School, Boston, Massachusetts. Electronic address:
Background: Physiologic volar melanotic macules (P-VMM) are understudied. Trauma has been suggested as a predisposing factor. Little has been published over the last several decades.
View Article and Find Full Text PDFCureus
October 2024
Internal Medicine, Jinnah Postgraduate Medical Centre, Karachi, PAK.
Gastrointestinal (GI) diseases can present with several extraintestinal manifestations, and cutaneous signs and symptoms are most frequent. Although conventionally GI and skin are considered two entirely separate organ systems, they are closely correlated in origin. An increasing amount of data highlights the complex relationship between GI and dermatological conditions.
View Article and Find Full Text PDFExp Dermatol
October 2024
Oncologic Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
World J Surg Oncol
July 2024
Department of Pharmacy, Tongji Medical College, The Central Hospital of Wuhan, Huazhong University of Science and Technology, Wuhan, Hubei, China.
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