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Distribution of Virulence-Associated and Aminoglycoside Resistance Genes Among Clinical Isolates of in the Southeast of Iran, During 2019-2023: A Cross-Sectional Study.
Health Sci Rep
December 2024
Department of Microbiology School of Medicine, Zabol University of Medical Sciences Zabol Iran.
Background And Aims: (), included in the World Health Organization's list of critical priority pathogens, is considered a serious threat to public health. The present study aims to investigate the prevalence of virulence-associated and aminoglycoside resistance genes in clinical isolates of .
Methods: This cross-sectional study was carried out on 88 clinical isolates of .
Evaluation of virulence genes in Proteus strains isolated from diabetic foot infections and urinary tract infections.
J Infect Dev Ctries
October 2024
Department of Medical Microbiology, Gülhane Faculty of Medicine, University of Health Sciences, Ankara, Türkiye.
Article Synopsis
- The study aimed to investigate the presence of virulence genes in Proteus mirabilis and Proteus vulgaris strains obtained from patients with diabetic foot infections (DFIs) and urinary tract infections (UTIs).
- A total of 78 isolates were analyzed, with the majority being identified through a specialized mass spectrometry technique and the presence of specific virulence genes assessed using PCR.
- Results indicated that most virulence genes were more commonly found in UTI isolates compared to DFI isolates, highlighting potential differences in the pathogenicity of these bacteria in different infection types.
Virulence-associated variants in sequence type 93 are less likely to be associated with population structure compared to independent rare mutations.
Microbiol Spectr
January 2025
Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
is a pathogenic yeast that is the causative agent of cryptococcal meningitis. While it is well known that the genotype of impacts patient outcomes, the reason for this association has not been well elucidated. In this study, we examined the relationship between two subpopulations in the sequence type 93 clade of : ST93A and ST93B.
View Article and Find Full Text PDFGenome characterization of in Hainan Province, China.
Front Microbiol
October 2024
Clinical & Central Laboratory of Sanya People's Hospital, Sanya, China.
is an emerging marine zoonotic pathogen. In this study, we first reported the infections in patients and animals in Hainan Province, China. Currently, there is still relatively little known about the whole-genome characteristics of in most tropical regions, including in southern China.
View Article and Find Full Text PDFPolidocanol inhibits Enterococcus faecalis virulence factors by targeting fsr quorum sensing system.
BMC Microbiol
October 2024
Department of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.
Background: The wide spread of antimicrobial resistance in Enterococcus faecalis is a critical global concern, leading to increasingly limited treatment options. The fsr quorum sensing (QS) plays a critical role in the pathogenicity of E. faecalis, allowing bacteria to coordinate gene expression and regulate many virulence factors.
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